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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PCSK1
All Species:
15.15
Human Site:
T632
Identified Species:
27.78
UniProt:
P29120
Number Species:
12
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P29120
NP_000430.3
753
84152
T632
D
P
G
E
E
Q
P
T
Q
E
N
P
K
E
N
Chimpanzee
Pan troglodytes
XP_517645
753
84134
T632
D
P
G
E
E
Q
P
T
Q
E
N
P
K
E
N
Rhesus Macaque
Macaca mulatta
XP_001094068
794
86687
D632
T
H
Y
S
T
E
N
D
V
E
T
I
R
A
S
Dog
Lupus familis
XP_848637
753
84126
T632
D
L
G
E
E
Q
P
T
Q
D
N
L
K
K
N
Cat
Felis silvestris
Mouse
Mus musculus
P63239
753
84155
T632
N
V
V
E
K
R
P
T
Q
K
S
L
N
G
N
Rat
Rattus norvegicus
P28840
752
84102
P631
V
N
V
V
E
E
K
P
T
Q
N
S
L
N
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512273
758
84714
T637
T
D
L
A
E
D
E
T
T
P
D
T
L
S
E
Chicken
Gallus gallus
Frog
Xenopus laevis
P29119
783
86425
Q605
E
E
G
Y
F
L
H
Q
K
S
C
I
K
S
C
Zebra Danio
Brachydanio rerio
NP_001131134
755
84185
T636
M
M
K
Q
E
A
P
T
P
A
L
K
P
E
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P30430
1101
120975
D892
A
E
E
D
E
Q
D
D
E
V
T
R
G
P
V
Honey Bee
Apis mellifera
XP_393918
714
80231
E597
D
D
S
T
A
G
F
E
K
W
K
F
M
S
V
Nematode Worm
Caenorhab. elegans
P51559
943
103128
G805
G
Y
Y
I
N
A
V
G
K
C
D
L
C
D
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P13134
814
89984
T654
T
S
A
I
P
Q
T
T
T
A
S
T
D
P
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
42.9
96.4
N.A.
92.5
92.6
N.A.
78.2
N.A.
41.2
72.5
N.A.
32.6
44
33.8
N.A.
Protein Similarity:
100
100
58.5
97.8
N.A.
96.4
96.1
N.A.
84.4
N.A.
57.4
84.1
N.A.
45.7
58.7
49.4
N.A.
P-Site Identity:
100
100
6.6
73.3
N.A.
33.3
13.3
N.A.
13.3
N.A.
13.3
26.6
N.A.
13.3
6.6
0
N.A.
P-Site Similarity:
100
100
26.6
86.6
N.A.
66.6
26.6
N.A.
20
N.A.
26.6
33.3
N.A.
26.6
13.3
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
29.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
49.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
8
8
16
0
0
0
16
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
8
0
8
0
8
% C
% Asp:
31
16
0
8
0
8
8
16
0
8
16
0
8
8
8
% D
% Glu:
8
16
8
31
54
16
8
8
8
24
0
0
0
24
8
% E
% Phe:
0
0
0
0
8
0
8
0
0
0
0
8
0
0
0
% F
% Gly:
8
0
31
0
0
8
0
8
0
0
0
0
8
8
8
% G
% His:
0
8
0
0
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
16
0
0
0
0
0
0
0
16
0
0
8
% I
% Lys:
0
0
8
0
8
0
8
0
24
8
8
8
31
8
0
% K
% Leu:
0
8
8
0
0
8
0
0
0
0
8
24
16
0
0
% L
% Met:
8
8
0
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
8
8
0
0
8
0
8
0
0
0
31
0
8
8
31
% N
% Pro:
0
16
0
0
8
0
39
8
8
8
0
16
8
16
0
% P
% Gln:
0
0
0
8
0
39
0
8
31
8
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
8
0
0
0
0
0
8
8
0
0
% R
% Ser:
0
8
8
8
0
0
0
0
0
8
16
8
0
24
16
% S
% Thr:
24
0
0
8
8
0
8
54
24
0
16
16
0
0
0
% T
% Val:
8
8
16
8
0
0
8
0
8
8
0
0
0
0
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% W
% Tyr:
0
8
16
8
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _