KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PCSK6
All Species:
13.94
Human Site:
S645
Identified Species:
27.88
UniProt:
P29122
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P29122
NP_002561.1
969
106420
S645
H
T
F
S
A
H
Q
S
R
S
R
M
L
E
L
Chimpanzee
Pan troglodytes
XP_001146976
986
108574
S662
H
T
F
S
A
H
Q
S
R
S
R
M
L
E
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_545820
1355
149403
S1031
T
T
F
S
S
H
Q
S
R
S
R
M
L
E
L
Cat
Felis silvestris
Mouse
Mus musculus
Q04592
1877
209270
K613
S
P
T
N
E
F
P
K
V
E
R
F
R
Y
S
Rat
Rattus norvegicus
Q63415
937
104035
S626
R
T
F
S
S
H
Q
S
R
S
R
M
L
E
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507677
642
72067
D354
N
S
Q
L
T
W
R
D
V
Q
H
L
L
V
K
Chicken
Gallus gallus
XP_413892
919
101787
P613
N
T
P
G
A
P
Q
P
R
T
R
T
L
E
V
Frog
Xenopus laevis
P29119
783
86425
C495
R
L
S
L
S
Y
N
C
R
G
D
L
A
I
Y
Zebra Danio
Brachydanio rerio
NP_001077298
917
101996
R616
S
F
R
S
D
K
P
R
S
L
A
E
S
Q
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P30432
1679
183351
S864
K
S
E
L
L
N
S
S
P
Q
L
R
S
P
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P51559
943
103128
A642
P
V
Y
S
A
T
P
A
T
S
Q
G
V
L
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P13134
814
89984
L526
R
G
T
T
T
V
D
L
I
S
P
A
G
I
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.3
N.A.
64.5
N.A.
31.8
89.7
N.A.
58.9
69.2
40.7
55.9
N.A.
30.4
N.A.
35.5
N.A.
Protein Similarity:
100
91.5
N.A.
67.4
N.A.
39.4
92.7
N.A.
62.5
78.6
52
68.2
N.A.
40
N.A.
48.8
N.A.
P-Site Identity:
100
100
N.A.
86.6
N.A.
6.6
86.6
N.A.
6.6
46.6
6.6
6.6
N.A.
6.6
N.A.
20
N.A.
P-Site Similarity:
100
100
N.A.
93.3
N.A.
13.3
93.3
N.A.
33.3
66.6
26.6
13.3
N.A.
20
N.A.
46.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
34
0
0
9
0
0
9
9
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
9
0
9
9
0
0
9
0
0
0
0
% D
% Glu:
0
0
9
0
9
0
0
0
0
9
0
9
0
42
0
% E
% Phe:
0
9
34
0
0
9
0
0
0
0
0
9
0
0
0
% F
% Gly:
0
9
0
9
0
0
0
0
0
9
0
9
9
0
0
% G
% His:
17
0
0
0
0
34
0
0
0
0
9
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
9
0
0
0
0
17
9
% I
% Lys:
9
0
0
0
0
9
0
9
0
0
0
0
0
0
9
% K
% Leu:
0
9
0
25
9
0
0
9
0
9
9
17
50
9
34
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
34
0
0
0
% M
% Asn:
17
0
0
9
0
9
9
0
0
0
0
0
0
0
0
% N
% Pro:
9
9
9
0
0
9
25
9
9
0
9
0
0
9
9
% P
% Gln:
0
0
9
0
0
0
42
0
0
17
9
0
0
9
0
% Q
% Arg:
25
0
9
0
0
0
9
9
50
0
50
9
9
0
0
% R
% Ser:
17
17
9
50
25
0
9
42
9
50
0
0
17
0
25
% S
% Thr:
9
42
17
9
17
9
0
0
9
9
0
9
0
0
0
% T
% Val:
0
9
0
0
0
9
0
0
17
0
0
0
9
9
9
% V
% Trp:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
0
0
9
0
0
0
0
0
0
0
9
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _