KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PCSK6
All Species:
6.97
Human Site:
S722
Identified Species:
13.94
UniProt:
P29122
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P29122
NP_002561.1
969
106420
S722
C
V
H
F
S
L
G
S
V
K
T
S
R
K
C
Chimpanzee
Pan troglodytes
XP_001146976
986
108574
S739
C
V
H
F
S
L
G
S
V
K
T
S
R
K
C
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_545820
1355
149403
N1108
C
V
H
F
S
L
G
N
V
K
T
S
R
K
C
Cat
Felis silvestris
Mouse
Mus musculus
Q04592
1877
209270
W1568
C
L
S
C
R
P
G
W
F
Q
L
G
K
E
C
Rat
Rattus norvegicus
Q63415
937
104035
T693
F
S
L
G
N
S
K
T
N
R
K
C
V
S
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507677
642
72067
P420
I
G
T
S
D
K
R
P
R
I
I
P
I
E
Q
Chicken
Gallus gallus
XP_413892
919
101787
T679
Y
S
L
G
S
V
K
T
G
R
M
C
V
S
S
Frog
Xenopus laevis
P29119
783
86425
L561
N
N
N
N
Y
G
T
L
T
Q
F
V
L
V
L
Zebra Danio
Brachydanio rerio
NP_001077298
917
101996
C685
F
R
D
D
K
K
R
C
K
K
C
F
P
L
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P30432
1679
183351
S988
P
T
Q
C
V
A
C
S
H
Y
R
L
D
N
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P51559
943
103128
G710
L
R
N
K
G
G
S
G
F
K
C
V
Q
K
C
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P13134
814
89984
G592
S
W
R
L
K
L
F
G
E
S
I
D
S
S
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.3
N.A.
64.5
N.A.
31.8
89.7
N.A.
58.9
69.2
40.7
55.9
N.A.
30.4
N.A.
35.5
N.A.
Protein Similarity:
100
91.5
N.A.
67.4
N.A.
39.4
92.7
N.A.
62.5
78.6
52
68.2
N.A.
40
N.A.
48.8
N.A.
P-Site Identity:
100
100
N.A.
93.3
N.A.
20
0
N.A.
0
6.6
0
13.3
N.A.
6.6
N.A.
20
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
46.6
20
N.A.
6.6
26.6
13.3
13.3
N.A.
6.6
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% A
% Cys:
34
0
0
17
0
0
9
9
0
0
17
17
0
0
50
% C
% Asp:
0
0
9
9
9
0
0
0
0
0
0
9
9
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
9
0
0
0
0
17
9
% E
% Phe:
17
0
0
25
0
0
9
0
17
0
9
9
0
0
0
% F
% Gly:
0
9
0
17
9
17
34
17
9
0
0
9
0
0
0
% G
% His:
0
0
25
0
0
0
0
0
9
0
0
0
0
0
0
% H
% Ile:
9
0
0
0
0
0
0
0
0
9
17
0
9
0
0
% I
% Lys:
0
0
0
9
17
17
17
0
9
42
9
0
9
34
9
% K
% Leu:
9
9
17
9
0
34
0
9
0
0
9
9
9
9
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% M
% Asn:
9
9
17
9
9
0
0
9
9
0
0
0
0
9
0
% N
% Pro:
9
0
0
0
0
9
0
9
0
0
0
9
9
0
0
% P
% Gln:
0
0
9
0
0
0
0
0
0
17
0
0
9
0
9
% Q
% Arg:
0
17
9
0
9
0
17
0
9
17
9
0
25
0
0
% R
% Ser:
9
17
9
9
34
9
9
25
0
9
0
25
9
25
9
% S
% Thr:
0
9
9
0
0
0
9
17
9
0
25
0
0
0
9
% T
% Val:
0
25
0
0
9
9
0
0
25
0
0
17
17
9
0
% V
% Trp:
0
9
0
0
0
0
0
9
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
9
0
0
0
0
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _