KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PCSK6
All Species:
12.73
Human Site:
T741
Identified Species:
25.45
UniProt:
P29122
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P29122
NP_002561.1
969
106420
T741
P
L
G
Y
F
G
D
T
A
A
R
R
C
R
R
Chimpanzee
Pan troglodytes
XP_001146976
986
108574
T758
P
L
G
Y
F
G
D
T
A
A
R
R
C
R
R
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_545820
1355
149403
T1127
P
L
G
Y
F
G
D
T
A
A
R
R
C
R
R
Cat
Felis silvestris
Mouse
Mus musculus
Q04592
1877
209270
S1587
R
D
G
Y
Y
G
E
S
T
S
G
R
C
E
K
Rat
Rattus norvegicus
Q63415
937
104035
R712
Y
F
G
D
T
A
A
R
R
C
R
R
C
H
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507677
642
72067
A439
T
T
L
T
N
A
C
A
D
H
Y
D
Q
H
V
Chicken
Gallus gallus
XP_413892
919
101787
R698
F
F
G
D
K
A
A
R
R
C
R
R
C
Y
K
Frog
Xenopus laevis
P29119
783
86425
F580
S
E
G
L
S
R
K
F
D
G
D
G
S
R
N
Zebra Danio
Brachydanio rerio
NP_001077298
917
101996
S704
G
S
R
S
D
Q
C
S
T
C
R
P
G
L
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P30432
1679
183351
N1007
C
P
P
R
S
F
P
N
Q
V
G
I
C
W
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P51559
943
103128
K729
Y
L
D
G
D
K
C
K
M
C
S
S
H
C
H
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P13134
814
89984
E611
V
F
G
N
D
K
E
E
V
E
P
A
A
T
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.3
N.A.
64.5
N.A.
31.8
89.7
N.A.
58.9
69.2
40.7
55.9
N.A.
30.4
N.A.
35.5
N.A.
Protein Similarity:
100
91.5
N.A.
67.4
N.A.
39.4
92.7
N.A.
62.5
78.6
52
68.2
N.A.
40
N.A.
48.8
N.A.
P-Site Identity:
100
100
N.A.
100
N.A.
33.3
26.6
N.A.
0
26.6
13.3
6.6
N.A.
6.6
N.A.
6.6
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
66.6
33.3
N.A.
0
33.3
13.3
13.3
N.A.
6.6
N.A.
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
25
17
9
25
25
0
9
9
0
0
% A
% Cys:
9
0
0
0
0
0
25
0
0
34
0
0
59
9
0
% C
% Asp:
0
9
9
17
25
0
25
0
17
0
9
9
0
0
0
% D
% Glu:
0
9
0
0
0
0
17
9
0
9
0
0
0
9
9
% E
% Phe:
9
25
0
0
25
9
0
9
0
0
0
0
0
0
0
% F
% Gly:
9
0
67
9
0
34
0
0
0
9
17
9
9
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
9
0
0
9
17
9
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% I
% Lys:
0
0
0
0
9
17
9
9
0
0
0
0
0
0
25
% K
% Leu:
0
34
9
9
0
0
0
0
0
0
0
0
0
9
0
% L
% Met:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% M
% Asn:
0
0
0
9
9
0
0
9
0
0
0
0
0
0
9
% N
% Pro:
25
9
9
0
0
0
9
0
0
0
9
9
0
0
9
% P
% Gln:
0
0
0
0
0
9
0
0
9
0
0
0
9
0
0
% Q
% Arg:
9
0
9
9
0
9
0
17
17
0
50
50
0
34
25
% R
% Ser:
9
9
0
9
17
0
0
17
0
9
9
9
9
0
0
% S
% Thr:
9
9
0
9
9
0
0
25
17
0
0
0
0
9
0
% T
% Val:
9
0
0
0
0
0
0
0
9
9
0
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% W
% Tyr:
17
0
0
34
9
0
0
0
0
0
9
0
0
9
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _