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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PCSK6
All Species:
7.27
Human Site:
T815
Identified Species:
14.55
UniProt:
P29122
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P29122
NP_002561.1
969
106420
T815
V
D
E
P
E
K
C
T
V
C
K
E
G
F
S
Chimpanzee
Pan troglodytes
XP_001146976
986
108574
T832
V
D
E
P
E
K
C
T
V
C
K
E
G
F
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_545820
1355
149403
I1201
V
D
E
P
E
R
C
I
V
C
K
E
G
F
S
Cat
Felis silvestris
Mouse
Mus musculus
Q04592
1877
209270
C1661
S
G
K
E
A
W
S
C
L
S
C
V
W
S
Y
Rat
Rattus norvegicus
Q63415
937
104035
K786
P
E
K
S
T
V
C
K
E
G
F
S
L
A
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507677
642
72067
T513
E
K
A
E
G
E
W
T
L
E
I
H
D
M
P
Chicken
Gallus gallus
XP_413892
919
101787
K772
P
D
K
C
T
A
C
K
D
G
F
S
L
V
G
Frog
Xenopus laevis
P29119
783
86425
I654
A
T
C
K
G
T
T
I
N
D
C
L
T
C
P
Zebra Danio
Brachydanio rerio
NP_001077298
917
101996
G778
E
P
G
T
Y
Y
N
G
H
R
R
A
C
E
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P30432
1679
183351
T1081
Q
D
H
P
E
Y
C
T
S
C
D
H
H
L
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P51559
943
103128
A803
G
D
G
Y
Y
I
N
A
V
G
K
C
D
L
C
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P13134
814
89984
L685
H
Y
F
L
T
I
F
L
I
G
A
T
F
L
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.3
N.A.
64.5
N.A.
31.8
89.7
N.A.
58.9
69.2
40.7
55.9
N.A.
30.4
N.A.
35.5
N.A.
Protein Similarity:
100
91.5
N.A.
67.4
N.A.
39.4
92.7
N.A.
62.5
78.6
52
68.2
N.A.
40
N.A.
48.8
N.A.
P-Site Identity:
100
100
N.A.
86.6
N.A.
0
6.6
N.A.
6.6
13.3
0
0
N.A.
40
N.A.
20
N.A.
P-Site Similarity:
100
100
N.A.
93.3
N.A.
13.3
20
N.A.
20
20
0
6.6
N.A.
40
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
9
0
9
9
0
9
0
0
9
9
0
9
0
% A
% Cys:
0
0
9
9
0
0
50
9
0
34
17
9
9
9
9
% C
% Asp:
0
50
0
0
0
0
0
0
9
9
9
0
17
0
0
% D
% Glu:
17
9
25
17
34
9
0
0
9
9
0
25
0
9
0
% E
% Phe:
0
0
9
0
0
0
9
0
0
0
17
0
9
25
0
% F
% Gly:
9
9
17
0
17
0
0
9
0
34
0
0
25
0
9
% G
% His:
9
0
9
0
0
0
0
0
9
0
0
17
9
0
0
% H
% Ile:
0
0
0
0
0
17
0
17
9
0
9
0
0
0
0
% I
% Lys:
0
9
25
9
0
17
0
17
0
0
34
0
0
0
9
% K
% Leu:
0
0
0
9
0
0
0
9
17
0
0
9
17
25
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% M
% Asn:
0
0
0
0
0
0
17
0
9
0
0
0
0
0
0
% N
% Pro:
17
9
0
34
0
0
0
0
0
0
0
0
0
0
17
% P
% Gln:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
9
0
0
0
9
9
0
0
0
9
% R
% Ser:
9
0
0
9
0
0
9
0
9
9
0
17
0
9
25
% S
% Thr:
0
9
0
9
25
9
9
34
0
0
0
9
9
0
0
% T
% Val:
25
0
0
0
0
9
0
0
34
0
0
9
0
9
17
% V
% Trp:
0
0
0
0
0
9
9
0
0
0
0
0
9
0
0
% W
% Tyr:
0
9
0
9
17
17
0
0
0
0
0
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _