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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PCSK6
All Species:
30
Human Site:
Y106
Identified Species:
60
UniProt:
P29122
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P29122
NP_002561.1
969
106420
Y106
Q
I
G
N
L
E
D
Y
Y
H
F
Y
H
S
K
Chimpanzee
Pan troglodytes
XP_001146976
986
108574
Y123
R
I
G
N
L
E
D
Y
Y
H
F
Y
H
S
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_545820
1355
149403
Y492
R
I
G
N
L
E
D
Y
Y
H
F
Y
H
S
K
Cat
Felis silvestris
Mouse
Mus musculus
Q04592
1877
209270
Y73
Q
I
G
A
L
K
D
Y
Y
H
F
Y
H
S
R
Rat
Rattus norvegicus
Q63415
937
104035
Y89
Q
I
G
N
L
D
D
Y
Y
H
F
Y
H
S
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507677
642
72067
Chicken
Gallus gallus
XP_413892
919
101787
Y74
S
I
G
S
L
E
N
Y
Y
H
F
H
H
S
K
Frog
Xenopus laevis
P29119
783
86425
Zebra Danio
Brachydanio rerio
NP_001077298
917
101996
Y66
Q
I
G
D
L
K
D
Y
Y
H
F
F
H
S
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P30432
1679
183351
Y275
Q
I
G
S
L
D
N
Y
Y
L
F
Q
H
H
H
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P51559
943
103128
H74
G
D
P
F
L
D
T
H
Y
F
L
Y
H
S
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P13134
814
89984
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.3
N.A.
64.5
N.A.
31.8
89.7
N.A.
58.9
69.2
40.7
55.9
N.A.
30.4
N.A.
35.5
N.A.
Protein Similarity:
100
91.5
N.A.
67.4
N.A.
39.4
92.7
N.A.
62.5
78.6
52
68.2
N.A.
40
N.A.
48.8
N.A.
P-Site Identity:
100
93.3
N.A.
93.3
N.A.
80
93.3
N.A.
0
73.3
0
73.3
N.A.
53.3
N.A.
33.3
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
93.3
100
N.A.
0
93.3
0
100
N.A.
73.3
N.A.
53.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
9
0
25
50
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
34
0
0
0
0
0
0
0
0
9
% E
% Phe:
0
0
0
9
0
0
0
0
0
9
67
9
0
0
0
% F
% Gly:
9
0
67
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
9
0
59
0
9
75
9
9
% H
% Ile:
0
67
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
17
0
0
0
0
0
0
0
0
42
% K
% Leu:
0
0
0
0
75
0
0
0
0
9
9
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
34
0
0
17
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
42
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% Q
% Arg:
17
0
0
0
0
0
0
0
0
0
0
0
0
0
17
% R
% Ser:
9
0
0
17
0
0
0
0
0
0
0
0
0
67
0
% S
% Thr:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
67
75
0
0
50
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _