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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PCSK6
All Species:
35.45
Human Site:
Y194
Identified Species:
70.91
UniProt:
P29122
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P29122
NP_002561.1
969
106420
Y194
Q
A
A
W
K
R
G
Y
T
G
K
N
V
V
V
Chimpanzee
Pan troglodytes
XP_001146976
986
108574
Y211
Q
A
A
W
K
R
G
Y
T
G
K
N
V
V
V
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_545820
1355
149403
Y580
Q
A
A
W
K
K
G
Y
T
G
K
N
V
V
V
Cat
Felis silvestris
Mouse
Mus musculus
Q04592
1877
209270
Y162
E
G
A
W
K
R
G
Y
T
G
K
N
I
V
V
Rat
Rattus norvegicus
Q63415
937
104035
Y175
Q
A
A
W
K
R
G
Y
T
G
K
N
V
V
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507677
642
72067
Chicken
Gallus gallus
XP_413892
919
101787
Y162
V
A
A
W
Q
R
G
Y
T
G
R
N
V
V
V
Frog
Xenopus laevis
P29119
783
86425
Y50
A
D
R
L
C
K
K
Y
G
F
I
N
H
G
L
Zebra Danio
Brachydanio rerio
NP_001077298
917
101996
Y165
V
G
A
W
K
R
G
Y
T
G
K
D
V
V
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P30432
1679
183351
Y406
G
P
A
W
Q
K
G
Y
T
G
K
G
V
V
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P51559
943
103128
Y191
R
Q
A
W
L
Q
G
Y
A
G
R
N
V
S
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P13134
814
89984
S81
L
L
K
L
G
K
R
S
S
L
E
E
L
Q
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.3
N.A.
64.5
N.A.
31.8
89.7
N.A.
58.9
69.2
40.7
55.9
N.A.
30.4
N.A.
35.5
N.A.
Protein Similarity:
100
91.5
N.A.
67.4
N.A.
39.4
92.7
N.A.
62.5
78.6
52
68.2
N.A.
40
N.A.
48.8
N.A.
P-Site Identity:
100
100
N.A.
93.3
N.A.
80
100
N.A.
0
80
13.3
80
N.A.
66.6
N.A.
53.3
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
93.3
100
N.A.
0
93.3
26.6
86.6
N.A.
80
N.A.
73.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
42
75
0
0
0
0
0
9
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
0
0
0
0
0
0
0
0
9
0
0
0
% D
% Glu:
9
0
0
0
0
0
0
0
0
0
9
9
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% F
% Gly:
9
17
0
0
9
0
75
0
9
75
0
9
0
9
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
9
0
9
0
0
% I
% Lys:
0
0
9
0
50
34
9
0
0
0
59
0
0
0
0
% K
% Leu:
9
9
0
17
9
0
0
0
0
9
0
0
9
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
67
0
0
0
% N
% Pro:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
34
9
0
0
17
9
0
0
0
0
0
0
0
9
0
% Q
% Arg:
9
0
9
0
0
50
9
0
0
0
17
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
9
9
0
0
0
0
9
0
% S
% Thr:
0
0
0
0
0
0
0
0
67
0
0
0
0
0
0
% T
% Val:
17
0
0
0
0
0
0
0
0
0
0
0
67
67
75
% V
% Trp:
0
0
0
75
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
84
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _