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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PCSK6
All Species:
9.7
Human Site:
Y70
Identified Species:
19.39
UniProt:
P29122
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P29122
NP_002561.1
969
106420
Y70
A
P
P
P
R
P
V
Y
T
N
H
W
A
V
Q
Chimpanzee
Pan troglodytes
XP_001146976
986
108574
L94
G
G
F
P
K
P
G
L
A
G
Q
R
P
G
A
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_545820
1355
149403
A197
A
F
L
E
Q
P
L
A
A
N
R
S
L
V
L
Cat
Felis silvestris
Mouse
Mus musculus
Q04592
1877
209270
Y37
P
V
C
R
T
R
V
Y
T
N
H
W
A
V
K
Rat
Rattus norvegicus
Q63415
937
104035
Y53
L
P
P
P
R
P
V
Y
T
N
H
W
A
V
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507677
642
72067
Chicken
Gallus gallus
XP_413892
919
101787
L44
R
E
A
G
I
P
L
L
R
P
R
P
R
R
R
Frog
Xenopus laevis
P29119
783
86425
Zebra Danio
Brachydanio rerio
NP_001077298
917
101996
W34
A
R
I
Y
T
N
H
W
A
V
R
I
A
G
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P30432
1679
183351
Y239
S
I
P
E
E
A
I
Y
T
N
E
F
A
V
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P51559
943
103128
H41
G
A
C
G
E
P
I
H
T
V
I
R
L
A
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P13134
814
89984
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.3
N.A.
64.5
N.A.
31.8
89.7
N.A.
58.9
69.2
40.7
55.9
N.A.
30.4
N.A.
35.5
N.A.
Protein Similarity:
100
91.5
N.A.
67.4
N.A.
39.4
92.7
N.A.
62.5
78.6
52
68.2
N.A.
40
N.A.
48.8
N.A.
P-Site Identity:
100
13.3
N.A.
26.6
N.A.
53.3
93.3
N.A.
0
6.6
0
13.3
N.A.
40
N.A.
13.3
N.A.
P-Site Similarity:
100
20
N.A.
40
N.A.
60
93.3
N.A.
0
20
0
20
N.A.
60
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
25
9
9
0
0
9
0
9
25
0
0
0
42
9
9
% A
% Cys:
0
0
17
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
9
0
17
17
0
0
0
0
0
9
0
0
0
0
% E
% Phe:
0
9
9
0
0
0
0
0
0
0
0
9
0
0
0
% F
% Gly:
17
9
0
17
0
0
9
0
0
9
0
0
0
17
9
% G
% His:
0
0
0
0
0
0
9
9
0
0
25
0
0
0
0
% H
% Ile:
0
9
9
0
9
0
17
0
0
0
9
9
0
0
0
% I
% Lys:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
17
% K
% Leu:
9
0
9
0
0
0
17
17
0
0
0
0
17
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
9
0
0
0
42
0
0
0
0
9
% N
% Pro:
9
17
25
25
0
50
0
0
0
9
0
9
9
0
0
% P
% Gln:
0
0
0
0
9
0
0
0
0
0
9
0
0
0
17
% Q
% Arg:
9
9
0
9
17
9
0
0
9
0
25
17
9
9
9
% R
% Ser:
9
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% S
% Thr:
0
0
0
0
17
0
0
0
42
0
0
0
0
0
0
% T
% Val:
0
9
0
0
0
0
25
0
0
17
0
0
0
42
0
% V
% Trp:
0
0
0
0
0
0
0
9
0
0
0
25
0
0
0
% W
% Tyr:
0
0
0
9
0
0
0
34
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _