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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PCSK6
All Species:
21.82
Human Site:
Y886
Identified Species:
43.64
UniProt:
P29122
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P29122
NP_002561.1
969
106420
Y886
P
A
C
G
E
G
F
Y
P
E
E
M
P
G
L
Chimpanzee
Pan troglodytes
XP_001146976
986
108574
Y903
P
A
C
G
E
G
F
Y
P
E
E
M
P
G
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_545820
1355
149403
Y1272
P
A
C
G
E
G
F
Y
P
E
E
M
P
G
L
Cat
Felis silvestris
Mouse
Mus musculus
Q04592
1877
209270
Y1763
P
A
R
E
A
E
F
Y
E
H
T
K
T
A
L
Rat
Rattus norvegicus
Q63415
937
104035
Y854
P
A
C
G
E
G
F
Y
P
E
E
M
P
G
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507677
642
72067
P567
P
E
E
M
P
G
L
P
H
K
V
C
R
R
C
Chicken
Gallus gallus
XP_413892
919
101787
Y836
P
A
C
R
E
G
F
Y
P
A
D
S
H
G
L
Frog
Xenopus laevis
P29119
783
86425
S708
P
F
I
V
A
I
L
S
C
L
F
I
I
V
V
Zebra Danio
Brachydanio rerio
NP_001077298
917
101996
K837
A
D
N
G
D
V
Q
K
S
C
Q
K
C
N
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P30432
1679
183351
Y1151
I
S
C
P
D
G
F
Y
A
D
K
K
R
L
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P51559
943
103128
K859
W
Q
C
E
D
C
S
K
P
D
P
T
L
L
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P13134
814
89984
E739
T
S
G
I
T
E
P
E
E
V
E
D
F
D
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.3
N.A.
64.5
N.A.
31.8
89.7
N.A.
58.9
69.2
40.7
55.9
N.A.
30.4
N.A.
35.5
N.A.
Protein Similarity:
100
91.5
N.A.
67.4
N.A.
39.4
92.7
N.A.
62.5
78.6
52
68.2
N.A.
40
N.A.
48.8
N.A.
P-Site Identity:
100
100
N.A.
100
N.A.
33.3
100
N.A.
13.3
66.6
6.6
6.6
N.A.
26.6
N.A.
13.3
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
33.3
100
N.A.
20
73.3
20
20
N.A.
53.3
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
50
0
0
17
0
0
0
9
9
0
0
0
9
0
% A
% Cys:
0
0
59
0
0
9
0
0
9
9
0
9
9
0
9
% C
% Asp:
0
9
0
0
25
0
0
0
0
17
9
9
0
9
0
% D
% Glu:
0
9
9
17
42
17
0
9
17
34
42
0
0
0
9
% E
% Phe:
0
9
0
0
0
0
59
0
0
0
9
0
9
0
9
% F
% Gly:
0
0
9
42
0
59
0
0
0
0
0
0
0
42
0
% G
% His:
0
0
0
0
0
0
0
0
9
9
0
0
9
0
0
% H
% Ile:
9
0
9
9
0
9
0
0
0
0
0
9
9
0
9
% I
% Lys:
0
0
0
0
0
0
0
17
0
9
9
25
0
0
0
% K
% Leu:
0
0
0
0
0
0
17
0
0
9
0
0
9
17
50
% L
% Met:
0
0
0
9
0
0
0
0
0
0
0
34
0
0
0
% M
% Asn:
0
0
9
0
0
0
0
0
0
0
0
0
0
9
0
% N
% Pro:
67
0
0
9
9
0
9
9
50
0
9
0
34
0
9
% P
% Gln:
0
9
0
0
0
0
9
0
0
0
9
0
0
0
0
% Q
% Arg:
0
0
9
9
0
0
0
0
0
0
0
0
17
9
0
% R
% Ser:
0
17
0
0
0
0
9
9
9
0
0
9
0
0
0
% S
% Thr:
9
0
0
0
9
0
0
0
0
0
9
9
9
0
0
% T
% Val:
0
0
0
9
0
9
0
0
0
9
9
0
0
9
9
% V
% Trp:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
59
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _