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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TPP2
All Species:
30.61
Human Site:
S183
Identified Species:
51.79
UniProt:
P29144
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P29144
NP_003282.2
1249
138350
S183
S
Q
V
E
L
L
N
S
F
E
K
K
Y
S
D
Chimpanzee
Pan troglodytes
XP_001151602
1249
138350
S183
S
Q
V
E
L
L
N
S
F
E
K
K
Y
S
D
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q64514
1262
139860
S183
S
Q
V
E
L
L
N
S
F
E
K
K
Y
S
D
Rat
Rattus norvegicus
Q64560
1249
138274
S183
S
Q
V
E
L
L
N
S
F
E
K
K
Y
S
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513544
1367
152093
S288
S
Q
V
E
L
L
N
S
F
E
K
K
F
N
D
Chicken
Gallus gallus
XP_425591
1248
138209
S182
N
Q
V
E
L
L
N
S
F
E
K
K
Y
S
D
Frog
Xenopus laevis
NP_001085380
1261
139671
S182
S
Q
V
E
M
L
N
S
F
E
K
K
Y
C
D
Zebra Danio
Brachydanio rerio
XP_693179
595
63935
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V6K1
1441
158719
S280
F
E
L
E
M
L
N
S
Y
E
K
V
Y
G
D
Honey Bee
Apis mellifera
XP_395521
1450
161968
N183
A
R
V
E
I
L
N
N
I
E
K
K
Y
S
D
Nematode Worm
Caenorhab. elegans
Q09541
1374
151070
K233
A
C
K
V
D
F
L
K
S
M
A
S
V
A
D
Sea Urchin
Strong. purpuratus
XP_788834
1215
133209
N183
A
M
L
D
V
L
N
N
A
D
K
K
Y
S
D
Poplar Tree
Populus trichocarpa
XP_002318216
1299
143140
K205
N
R
I
D
L
L
R
K
Q
A
D
V
Y
D
D
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_193817
1380
152349
K285
S
K
V
D
F
L
K
K
Q
A
D
K
Y
E
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
N.A.
N.A.
N.A.
95.3
96.8
N.A.
81.2
86
80.4
37.7
N.A.
34
41.3
35
54.7
Protein Similarity:
100
99.7
N.A.
N.A.
N.A.
97.4
98.7
N.A.
86.6
94.6
91.3
43.1
N.A.
53
59.2
53.4
71.6
P-Site Identity:
100
100
N.A.
N.A.
N.A.
100
100
N.A.
86.6
93.3
86.6
0
N.A.
53.3
66.6
6.6
46.6
P-Site Similarity:
100
100
N.A.
N.A.
N.A.
100
100
N.A.
100
100
93.3
0
N.A.
80
93.3
20
86.6
Percent
Protein Identity:
38
N.A.
N.A.
37.4
N.A.
N.A.
Protein Similarity:
56.9
N.A.
N.A.
54.1
N.A.
N.A.
P-Site Identity:
26.6
N.A.
N.A.
40
N.A.
N.A.
P-Site Similarity:
53.3
N.A.
N.A.
53.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
22
0
0
0
0
0
0
0
8
15
8
0
0
8
0
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
0
0
0
22
8
0
0
0
0
8
15
0
0
8
93
% D
% Glu:
0
8
0
65
0
0
0
0
0
65
0
0
0
8
0
% E
% Phe:
8
0
0
0
8
8
0
0
50
0
0
0
8
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
8
0
0
0
8
0
0
0
0
0
0
% I
% Lys:
0
8
8
0
0
0
8
22
0
0
72
72
0
0
0
% K
% Leu:
0
0
15
0
50
86
8
0
0
0
0
0
0
0
0
% L
% Met:
0
8
0
0
15
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
15
0
0
0
0
0
72
15
0
0
0
0
0
8
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
50
0
0
0
0
0
0
15
0
0
0
0
0
0
% Q
% Arg:
0
15
0
0
0
0
8
0
0
0
0
0
0
0
0
% R
% Ser:
50
0
0
0
0
0
0
58
8
0
0
8
0
50
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
65
8
8
0
0
0
0
0
0
15
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
8
0
0
0
79
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _