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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TPP2
All Species:
21.82
Human Site:
S566
Identified Species:
36.92
UniProt:
P29144
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P29144
NP_003282.2
1249
138350
S566
T
E
N
S
E
K
I
S
L
Q
L
H
L
A
L
Chimpanzee
Pan troglodytes
XP_001151602
1249
138350
S566
T
E
N
S
E
K
I
S
L
Q
L
H
L
A
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q64514
1262
139860
S566
T
E
N
S
E
K
I
S
F
Q
L
H
L
A
L
Rat
Rattus norvegicus
Q64560
1249
138274
S566
T
E
N
S
E
K
I
S
F
Q
L
H
L
A
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513544
1367
152093
S671
T
D
N
S
E
R
I
S
L
Q
L
H
L
V
L
Chicken
Gallus gallus
XP_425591
1248
138209
S565
T
E
N
T
E
R
I
S
L
Q
L
H
L
A
L
Frog
Xenopus laevis
NP_001085380
1261
139671
I566
K
T
E
N
S
E
R
I
S
L
Q
L
H
L
A
Zebra Danio
Brachydanio rerio
XP_693179
595
63935
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V6K1
1441
158719
N670
A
D
P
K
D
K
F
N
F
N
V
R
L
N
L
Honey Bee
Apis mellifera
XP_395521
1450
161968
A573
T
D
P
T
L
K
I
A
F
N
L
K
L
T
L
Nematode Worm
Caenorhab. elegans
Q09541
1374
151070
L616
E
P
I
F
Q
N
H
L
S
D
N
N
L
P
A
Sea Urchin
Strong. purpuratus
XP_788834
1215
133209
A564
T
D
P
A
E
K
I
A
F
N
L
H
I
A
L
Poplar Tree
Populus trichocarpa
XP_002318216
1299
143140
V603
A
S
N
L
E
E
L
V
C
F
E
E
C
I
E
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_193817
1380
152349
V683
A
S
N
L
K
E
L
V
P
F
E
E
C
L
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
N.A.
N.A.
N.A.
95.3
96.8
N.A.
81.2
86
80.4
37.7
N.A.
34
41.3
35
54.7
Protein Similarity:
100
99.7
N.A.
N.A.
N.A.
97.4
98.7
N.A.
86.6
94.6
91.3
43.1
N.A.
53
59.2
53.4
71.6
P-Site Identity:
100
100
N.A.
N.A.
N.A.
93.3
93.3
N.A.
80
86.6
0
0
N.A.
20
40
6.6
53.3
P-Site Similarity:
100
100
N.A.
N.A.
N.A.
93.3
93.3
N.A.
93.3
100
13.3
0
N.A.
46.6
60
20
80
Percent
Protein Identity:
38
N.A.
N.A.
37.4
N.A.
N.A.
Protein Similarity:
56.9
N.A.
N.A.
54.1
N.A.
N.A.
P-Site Identity:
13.3
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
22
0
0
8
0
0
0
15
0
0
0
0
0
43
15
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
15
0
0
% C
% Asp:
0
29
0
0
8
0
0
0
0
8
0
0
0
0
0
% D
% Glu:
8
36
8
0
58
22
0
0
0
0
15
15
0
0
15
% E
% Phe:
0
0
0
8
0
0
8
0
36
15
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
50
8
0
0
% H
% Ile:
0
0
8
0
0
0
58
8
0
0
0
0
8
8
0
% I
% Lys:
8
0
0
8
8
50
0
0
0
0
0
8
0
0
0
% K
% Leu:
0
0
0
15
8
0
15
8
29
8
58
8
65
15
65
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
58
8
0
8
0
8
0
22
8
8
0
8
0
% N
% Pro:
0
8
22
0
0
0
0
0
8
0
0
0
0
8
0
% P
% Gln:
0
0
0
0
8
0
0
0
0
43
8
0
0
0
0
% Q
% Arg:
0
0
0
0
0
15
8
0
0
0
0
8
0
0
0
% R
% Ser:
0
15
0
36
8
0
0
43
15
0
0
0
0
0
0
% S
% Thr:
58
8
0
15
0
0
0
0
0
0
0
0
0
8
0
% T
% Val:
0
0
0
0
0
0
0
15
0
0
8
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _