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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TPP2
All Species:
14.85
Human Site:
T1000
Identified Species:
25.13
UniProt:
P29144
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P29144
NP_003282.2
1249
138350
T1000
L
I
P
P
P
T
K
T
K
N
G
S
K
D
K
Chimpanzee
Pan troglodytes
XP_001151602
1249
138350
T1000
L
I
P
P
P
T
K
T
K
N
G
S
K
D
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q64514
1262
139860
I1000
G
K
F
K
K
D
V
I
P
V
H
Y
Y
L
I
Rat
Rattus norvegicus
Q64560
1249
138274
T1000
L
I
P
P
P
T
K
T
K
N
G
S
K
D
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513544
1367
152093
I1105
G
K
F
K
K
D
V
I
P
V
H
Y
Y
L
I
Chicken
Gallus gallus
XP_425591
1248
138209
S999
L
I
P
S
P
S
K
S
K
N
G
N
K
E
K
Frog
Xenopus laevis
NP_001085380
1261
139671
I1001
G
K
F
K
K
D
V
I
S
V
H
Y
H
L
I
Zebra Danio
Brachydanio rerio
XP_693179
595
63935
L367
A
G
N
N
G
P
C
L
T
T
V
G
C
P
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V6K1
1441
158719
K1115
I
L
N
P
A
E
K
K
S
H
T
N
G
S
S
Honey Bee
Apis mellifera
XP_395521
1450
161968
P1008
F
K
Y
I
L
S
E
P
N
K
K
S
S
S
S
Nematode Worm
Caenorhab. elegans
Q09541
1374
151070
S1056
I
Y
F
L
S
E
Y
S
T
R
P
T
K
G
L
Sea Urchin
Strong. purpuratus
XP_788834
1215
133209
Y987
K
D
T
Y
P
F
V
Y
V
L
T
Q
S
P
H
Poplar Tree
Populus trichocarpa
XP_002318216
1299
143140
Y1041
P
A
S
Y
R
I
T
Y
V
V
P
P
N
K
V
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_193817
1380
152349
P1120
Y
P
I
S
Y
V
V
P
P
N
K
P
E
E
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
N.A.
N.A.
N.A.
95.3
96.8
N.A.
81.2
86
80.4
37.7
N.A.
34
41.3
35
54.7
Protein Similarity:
100
99.7
N.A.
N.A.
N.A.
97.4
98.7
N.A.
86.6
94.6
91.3
43.1
N.A.
53
59.2
53.4
71.6
P-Site Identity:
100
100
N.A.
N.A.
N.A.
0
100
N.A.
0
66.6
0
0
N.A.
13.3
6.6
6.6
6.6
P-Site Similarity:
100
100
N.A.
N.A.
N.A.
0
100
N.A.
0
93.3
0
0
N.A.
40
20
26.6
6.6
Percent
Protein Identity:
38
N.A.
N.A.
37.4
N.A.
N.A.
Protein Similarity:
56.9
N.A.
N.A.
54.1
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
0
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
8
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
8
0
0
0
0
0
8
0
0
% C
% Asp:
0
8
0
0
0
22
0
0
0
0
0
0
0
22
8
% D
% Glu:
0
0
0
0
0
15
8
0
0
0
0
0
8
15
0
% E
% Phe:
8
0
29
0
0
8
0
0
0
0
0
0
0
0
0
% F
% Gly:
22
8
0
0
8
0
0
0
0
0
29
8
8
8
8
% G
% His:
0
0
0
0
0
0
0
0
0
8
22
0
8
0
8
% H
% Ile:
15
29
8
8
0
8
0
22
0
0
0
0
0
0
22
% I
% Lys:
8
29
0
22
22
0
36
8
29
8
15
0
36
8
29
% K
% Leu:
29
8
0
8
8
0
0
8
0
8
0
0
0
22
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
15
8
0
0
0
0
8
36
0
15
8
0
0
% N
% Pro:
8
8
29
29
36
8
0
15
22
0
15
15
0
15
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% Q
% Arg:
0
0
0
0
8
0
0
0
0
8
0
0
0
0
0
% R
% Ser:
0
0
8
15
8
15
0
15
15
0
0
29
15
15
15
% S
% Thr:
0
0
8
0
0
22
8
22
15
8
15
8
0
0
0
% T
% Val:
0
0
0
0
0
8
36
0
15
29
8
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
8
8
15
8
0
8
15
0
0
0
22
15
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _