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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TPP2 All Species: 29.09
Human Site: Y1195 Identified Species: 49.23
UniProt: P29144 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P29144 NP_003282.2 1249 138350 Y1195 H A L V N K M Y G R G L K F A
Chimpanzee Pan troglodytes XP_001151602 1249 138350 Y1195 H A L V N K M Y G R G L K F A
Rhesus Macaque Macaca mulatta
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q64514 1262 139860 Y1208 H A L V N K M Y G R G L K F A
Rat Rattus norvegicus Q64560 1249 138274 Y1195 H A L V N K M Y G R G L K F A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513544 1367 152093 Y1313 H A L V N K M Y G R S L K F A
Chicken Gallus gallus XP_425591 1248 138209 Y1194 H A L V N K M Y G R G L K F A
Frog Xenopus laevis NP_001085380 1261 139671 Y1207 H A L A S K L Y G R G I K F A
Zebra Danio Brachydanio rerio XP_693179 595 63935 D544 A D D E D F A D G D T G V I D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V6K1 1441 158719 Y1387 H A Y A H G H Y G R M Y K Y V
Honey Bee Apis mellifera XP_395521 1450 161968 I1264 T G L L I Y N I E K S P Q F I
Nematode Worm Caenorhab. elegans Q09541 1374 151070 H1308 T A L I S A K H A A A L G Q F
Sea Urchin Strong. purpuratus XP_788834 1215 133209 T1164 A T A T T S S T T P T T S T T
Poplar Tree Populus trichocarpa XP_002318216 1299 143140 L1242 R E R R R G R L G A A L K A L
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_193817 1380 152349 L1323 R E K R L S R L G T A L K V L
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 N.A. N.A. N.A. 95.3 96.8 N.A. 81.2 86 80.4 37.7 N.A. 34 41.3 35 54.7
Protein Similarity: 100 99.7 N.A. N.A. N.A. 97.4 98.7 N.A. 86.6 94.6 91.3 43.1 N.A. 53 59.2 53.4 71.6
P-Site Identity: 100 100 N.A. N.A. N.A. 100 100 N.A. 93.3 100 73.3 6.6 N.A. 40 13.3 20 0
P-Site Similarity: 100 100 N.A. N.A. N.A. 100 100 N.A. 93.3 100 93.3 13.3 N.A. 53.3 33.3 40 0
Percent
Protein Identity: 38 N.A. N.A. 37.4 N.A. N.A.
Protein Similarity: 56.9 N.A. N.A. 54.1 N.A. N.A.
P-Site Identity: 20 N.A. N.A. 20 N.A. N.A.
P-Site Similarity: 20 N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 15 65 8 15 0 8 8 0 8 15 22 0 0 8 50 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 8 0 8 0 0 8 0 8 0 0 0 0 8 % D
% Glu: 0 15 0 8 0 0 0 0 8 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 8 0 0 0 0 0 0 0 58 8 % F
% Gly: 0 8 0 0 0 15 0 0 79 0 43 8 8 0 0 % G
% His: 58 0 0 0 8 0 8 8 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 8 8 0 0 8 0 0 0 8 0 8 8 % I
% Lys: 0 0 8 0 0 50 8 0 0 8 0 0 72 0 0 % K
% Leu: 0 0 65 8 8 0 8 15 0 0 0 65 0 0 15 % L
% Met: 0 0 0 0 0 0 43 0 0 0 8 0 0 0 0 % M
% Asn: 0 0 0 0 43 0 8 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 8 0 8 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 8 8 0 % Q
% Arg: 15 0 8 15 8 0 15 0 0 58 0 0 0 0 0 % R
% Ser: 0 0 0 0 15 15 8 0 0 0 15 0 8 0 0 % S
% Thr: 15 8 0 8 8 0 0 8 8 8 15 8 0 8 8 % T
% Val: 0 0 0 43 0 0 0 0 0 0 0 0 8 8 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 8 0 0 8 0 58 0 0 0 8 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _