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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TPP2
All Species:
29.09
Human Site:
Y1195
Identified Species:
49.23
UniProt:
P29144
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P29144
NP_003282.2
1249
138350
Y1195
H
A
L
V
N
K
M
Y
G
R
G
L
K
F
A
Chimpanzee
Pan troglodytes
XP_001151602
1249
138350
Y1195
H
A
L
V
N
K
M
Y
G
R
G
L
K
F
A
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q64514
1262
139860
Y1208
H
A
L
V
N
K
M
Y
G
R
G
L
K
F
A
Rat
Rattus norvegicus
Q64560
1249
138274
Y1195
H
A
L
V
N
K
M
Y
G
R
G
L
K
F
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513544
1367
152093
Y1313
H
A
L
V
N
K
M
Y
G
R
S
L
K
F
A
Chicken
Gallus gallus
XP_425591
1248
138209
Y1194
H
A
L
V
N
K
M
Y
G
R
G
L
K
F
A
Frog
Xenopus laevis
NP_001085380
1261
139671
Y1207
H
A
L
A
S
K
L
Y
G
R
G
I
K
F
A
Zebra Danio
Brachydanio rerio
XP_693179
595
63935
D544
A
D
D
E
D
F
A
D
G
D
T
G
V
I
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V6K1
1441
158719
Y1387
H
A
Y
A
H
G
H
Y
G
R
M
Y
K
Y
V
Honey Bee
Apis mellifera
XP_395521
1450
161968
I1264
T
G
L
L
I
Y
N
I
E
K
S
P
Q
F
I
Nematode Worm
Caenorhab. elegans
Q09541
1374
151070
H1308
T
A
L
I
S
A
K
H
A
A
A
L
G
Q
F
Sea Urchin
Strong. purpuratus
XP_788834
1215
133209
T1164
A
T
A
T
T
S
S
T
T
P
T
T
S
T
T
Poplar Tree
Populus trichocarpa
XP_002318216
1299
143140
L1242
R
E
R
R
R
G
R
L
G
A
A
L
K
A
L
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_193817
1380
152349
L1323
R
E
K
R
L
S
R
L
G
T
A
L
K
V
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
N.A.
N.A.
N.A.
95.3
96.8
N.A.
81.2
86
80.4
37.7
N.A.
34
41.3
35
54.7
Protein Similarity:
100
99.7
N.A.
N.A.
N.A.
97.4
98.7
N.A.
86.6
94.6
91.3
43.1
N.A.
53
59.2
53.4
71.6
P-Site Identity:
100
100
N.A.
N.A.
N.A.
100
100
N.A.
93.3
100
73.3
6.6
N.A.
40
13.3
20
0
P-Site Similarity:
100
100
N.A.
N.A.
N.A.
100
100
N.A.
93.3
100
93.3
13.3
N.A.
53.3
33.3
40
0
Percent
Protein Identity:
38
N.A.
N.A.
37.4
N.A.
N.A.
Protein Similarity:
56.9
N.A.
N.A.
54.1
N.A.
N.A.
P-Site Identity:
20
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
20
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
65
8
15
0
8
8
0
8
15
22
0
0
8
50
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
8
0
8
0
0
8
0
8
0
0
0
0
8
% D
% Glu:
0
15
0
8
0
0
0
0
8
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
8
0
0
0
0
0
0
0
58
8
% F
% Gly:
0
8
0
0
0
15
0
0
79
0
43
8
8
0
0
% G
% His:
58
0
0
0
8
0
8
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
8
0
0
8
0
0
0
8
0
8
8
% I
% Lys:
0
0
8
0
0
50
8
0
0
8
0
0
72
0
0
% K
% Leu:
0
0
65
8
8
0
8
15
0
0
0
65
0
0
15
% L
% Met:
0
0
0
0
0
0
43
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
0
0
43
0
8
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
8
0
8
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
8
8
0
% Q
% Arg:
15
0
8
15
8
0
15
0
0
58
0
0
0
0
0
% R
% Ser:
0
0
0
0
15
15
8
0
0
0
15
0
8
0
0
% S
% Thr:
15
8
0
8
8
0
0
8
8
8
15
8
0
8
8
% T
% Val:
0
0
0
43
0
0
0
0
0
0
0
0
8
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
8
0
58
0
0
0
8
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _