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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TPP2
All Species:
30.91
Human Site:
Y233
Identified Species:
52.31
UniProt:
P29144
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P29144
NP_003282.2
1249
138350
Y233
N
Y
K
E
A
Q
E
Y
G
S
F
G
T
A
E
Chimpanzee
Pan troglodytes
XP_001151602
1249
138350
Y233
N
Y
K
E
A
Q
E
Y
G
S
F
G
T
A
E
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q64514
1262
139860
Y233
N
Y
K
E
A
Q
E
Y
S
S
F
G
T
A
E
Rat
Rattus norvegicus
Q64560
1249
138274
Y233
N
Y
K
E
A
Q
E
Y
G
S
F
G
T
A
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513544
1367
152093
Y338
N
Y
K
E
A
Q
E
Y
G
S
F
G
T
S
E
Chicken
Gallus gallus
XP_425591
1248
138209
Y232
T
Y
K
E
A
Q
E
Y
G
S
F
G
T
S
E
Frog
Xenopus laevis
NP_001085380
1261
139671
F232
N
Y
R
E
T
Q
E
F
G
S
F
G
A
S
E
Zebra Danio
Brachydanio rerio
XP_693179
595
63935
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V6K1
1441
158719
H328
I
G
E
Y
S
R
T
H
E
T
R
N
V
D
D
Honey Bee
Apis mellifera
XP_395521
1450
161968
Y233
E
Y
T
I
T
R
Q
Y
A
P
L
I
P
E
D
Nematode Worm
Caenorhab. elegans
Q09541
1374
151070
Y283
T
F
R
E
T
G
D
Y
A
Y
L
T
N
K
D
Sea Urchin
Strong. purpuratus
XP_788834
1215
133209
K233
N
Y
K
E
D
H
Q
K
A
T
L
S
N
L
D
Poplar Tree
Populus trichocarpa
XP_002318216
1299
143140
Y261
N
Y
R
I
E
R
K
Y
G
V
F
S
K
L
D
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_193817
1380
152349
Y341
N
Y
R
I
E
R
K
Y
G
V
F
S
R
L
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
N.A.
N.A.
N.A.
95.3
96.8
N.A.
81.2
86
80.4
37.7
N.A.
34
41.3
35
54.7
Protein Similarity:
100
99.7
N.A.
N.A.
N.A.
97.4
98.7
N.A.
86.6
94.6
91.3
43.1
N.A.
53
59.2
53.4
71.6
P-Site Identity:
100
100
N.A.
N.A.
N.A.
93.3
100
N.A.
93.3
86.6
66.6
0
N.A.
0
13.3
13.3
26.6
P-Site Similarity:
100
100
N.A.
N.A.
N.A.
93.3
100
N.A.
100
93.3
86.6
0
N.A.
40
33.3
40
46.6
Percent
Protein Identity:
38
N.A.
N.A.
37.4
N.A.
N.A.
Protein Similarity:
56.9
N.A.
N.A.
54.1
N.A.
N.A.
P-Site Identity:
33.3
N.A.
N.A.
33.3
N.A.
N.A.
P-Site Similarity:
60
N.A.
N.A.
60
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
43
0
0
0
22
0
0
0
8
29
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
0
8
0
0
0
0
0
0
8
43
% D
% Glu:
8
0
8
65
15
0
50
0
8
0
0
0
0
8
50
% E
% Phe:
0
8
0
0
0
0
0
8
0
0
65
0
0
0
0
% F
% Gly:
0
8
0
0
0
8
0
0
58
0
0
50
0
0
0
% G
% His:
0
0
0
0
0
8
0
8
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
22
0
0
0
0
0
0
0
8
0
0
0
% I
% Lys:
0
0
50
0
0
0
15
8
0
0
0
0
8
8
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
22
0
0
22
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
65
0
0
0
0
0
0
0
0
0
0
8
15
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
8
0
0
8
0
0
% P
% Gln:
0
0
0
0
0
50
15
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
29
0
0
29
0
0
0
0
8
0
8
0
0
% R
% Ser:
0
0
0
0
8
0
0
0
8
50
0
22
0
22
0
% S
% Thr:
15
0
8
0
22
0
8
0
0
15
0
8
43
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
15
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
79
0
8
0
0
0
72
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _