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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TPP2
All Species:
41.21
Human Site:
Y249
Identified Species:
69.74
UniProt:
P29144
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P29144
NP_003282.2
1249
138350
Y249
L
N
Y
S
V
N
I
Y
D
D
G
N
L
L
S
Chimpanzee
Pan troglodytes
XP_001151602
1249
138350
Y249
L
N
Y
S
V
N
I
Y
D
D
G
N
L
L
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q64514
1262
139860
Y249
L
N
Y
S
V
N
I
Y
D
D
G
N
L
L
S
Rat
Rattus norvegicus
Q64560
1249
138274
Y249
L
N
Y
S
V
N
I
Y
D
D
G
N
L
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513544
1367
152093
Y354
L
N
Y
S
V
N
I
Y
D
E
G
N
L
L
S
Chicken
Gallus gallus
XP_425591
1248
138209
Y248
L
N
Y
S
V
N
I
Y
D
D
G
N
L
L
S
Frog
Xenopus laevis
NP_001085380
1261
139671
Y248
L
N
Y
S
V
N
I
Y
D
E
G
N
L
L
S
Zebra Danio
Brachydanio rerio
XP_693179
595
63935
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V6K1
1441
158719
H344
L
S
I
S
V
N
V
H
D
E
G
N
V
L
E
Honey Bee
Apis mellifera
XP_395521
1450
161968
H249
L
N
I
S
I
N
I
H
D
D
G
N
T
L
E
Nematode Worm
Caenorhab. elegans
Q09541
1374
151070
S299
V
V
Y
T
V
R
V
S
P
D
G
N
L
T
E
Sea Urchin
Strong. purpuratus
XP_788834
1215
133209
Y249
L
N
Y
S
V
N
I
Y
D
D
G
N
V
L
S
Poplar Tree
Populus trichocarpa
XP_002318216
1299
143140
Y277
C
T
F
V
L
N
V
Y
S
D
G
N
I
L
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_193817
1380
152349
Y357
C
S
F
V
A
N
V
Y
D
E
G
K
V
L
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
N.A.
N.A.
N.A.
95.3
96.8
N.A.
81.2
86
80.4
37.7
N.A.
34
41.3
35
54.7
Protein Similarity:
100
99.7
N.A.
N.A.
N.A.
97.4
98.7
N.A.
86.6
94.6
91.3
43.1
N.A.
53
59.2
53.4
71.6
P-Site Identity:
100
100
N.A.
N.A.
N.A.
100
100
N.A.
93.3
100
93.3
0
N.A.
53.3
66.6
40
93.3
P-Site Similarity:
100
100
N.A.
N.A.
N.A.
100
100
N.A.
100
100
100
0
N.A.
86.6
80
60
100
Percent
Protein Identity:
38
N.A.
N.A.
37.4
N.A.
N.A.
Protein Similarity:
56.9
N.A.
N.A.
54.1
N.A.
N.A.
P-Site Identity:
46.6
N.A.
N.A.
40
N.A.
N.A.
P-Site Similarity:
73.3
N.A.
N.A.
73.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
15
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
79
65
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
29
0
0
0
0
22
% E
% Phe:
0
0
15
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
93
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
15
0
0
0
0
0
0
0
% H
% Ile:
0
0
15
0
8
0
65
0
0
0
0
0
8
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% K
% Leu:
72
0
0
0
8
0
0
0
0
0
0
0
58
86
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
65
0
0
0
86
0
0
0
0
0
86
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
15
0
72
0
0
0
8
8
0
0
0
0
0
72
% S
% Thr:
0
8
0
8
0
0
0
0
0
0
0
0
8
8
0
% T
% Val:
8
8
0
15
72
0
29
0
0
0
0
0
22
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
65
0
0
0
0
72
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _