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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IMPA1
All Species:
35.15
Human Site:
S37
Identified Species:
55.24
UniProt:
P29218
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P29218
NP_001138350.1
277
30189
S37
E
M
N
V
M
L
K
S
S
P
V
D
L
V
T
Chimpanzee
Pan troglodytes
XP_001168821
277
30156
S37
E
M
N
V
M
L
K
S
S
P
V
D
L
V
T
Rhesus Macaque
Macaca mulatta
XP_001092596
277
30251
S37
E
M
N
V
M
L
K
S
S
P
V
D
L
V
T
Dog
Lupus familis
XP_535114
277
30225
S37
E
M
N
V
M
I
K
S
S
P
A
D
L
V
T
Cat
Felis silvestris
Mouse
Mus musculus
O55023
277
30418
S37
E
M
D
V
M
I
K
S
S
P
A
D
L
V
T
Rat
Rattus norvegicus
P97697
277
30493
S37
K
M
D
V
M
I
K
S
S
P
A
D
L
V
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508686
235
25995
N22
N
C
I
W
F
Y
V
N
Y
R
F
I
A
E
E
Chicken
Gallus gallus
XP_418310
278
30123
S37
E
K
S
I
M
I
K
S
S
P
V
D
L
V
T
Frog
Xenopus laevis
P29219
285
30711
L40
S
I
M
V
K
T
S
L
A
P
A
D
L
V
T
Zebra Danio
Brachydanio rerio
NP_001002745
282
30560
S37
D
L
K
I
M
C
K
S
S
S
V
D
L
V
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393191
272
29815
S36
P
K
D
A
M
T
K
S
C
E
V
D
L
V
T
Nematode Worm
Caenorhab. elegans
Q19420
285
30962
S43
E
S
K
V
D
T
K
S
S
N
T
D
L
V
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M8S8
271
29103
K38
E
T
K
H
V
E
H
K
G
Q
V
D
L
V
T
Baker's Yeast
Sacchar. cerevisiae
Q05533
292
32074
K41
N
F
C
S
Y
D
D
K
A
N
G
V
D
L
V
Red Bread Mold
Neurospora crassa
P11634
340
37305
I62
E
K
D
S
A
V
D
I
V
T
Q
T
D
E
D
Conservation
Percent
Protein Identity:
100
99.6
97.8
90.2
N.A.
86.2
84.8
N.A.
46.5
82
74.3
65.9
N.A.
N.A.
49
45.6
N.A.
Protein Similarity:
100
100
99.6
95.6
N.A.
94.2
93.8
N.A.
64.2
92.8
88.7
82.6
N.A.
N.A.
67.1
60.3
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
80
73.3
N.A.
0
73.3
40
60
N.A.
N.A.
53.3
60
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
6.6
93.3
53.3
80
N.A.
N.A.
60
60
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
40.7
36.3
30.5
Protein Similarity:
N.A.
N.A.
N.A.
61
55.1
46.4
P-Site Identity:
N.A.
N.A.
N.A.
40
0
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
13.3
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
7
0
0
0
14
0
27
0
7
0
0
% A
% Cys:
0
7
7
0
0
7
0
0
7
0
0
0
0
0
0
% C
% Asp:
7
0
27
0
7
7
14
0
0
0
0
80
14
0
7
% D
% Glu:
60
0
0
0
0
7
0
0
0
7
0
0
0
14
7
% E
% Phe:
0
7
0
0
7
0
0
0
0
0
7
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
7
0
7
0
0
0
0
% G
% His:
0
0
0
7
0
0
7
0
0
0
0
0
0
0
0
% H
% Ile:
0
7
7
14
0
27
0
7
0
0
0
7
0
0
0
% I
% Lys:
7
20
20
0
7
0
67
14
0
0
0
0
0
0
0
% K
% Leu:
0
7
0
0
0
20
0
7
0
0
0
0
80
7
0
% L
% Met:
0
40
7
0
60
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
14
0
27
0
0
0
0
7
0
14
0
0
0
0
0
% N
% Pro:
7
0
0
0
0
0
0
0
0
54
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
7
7
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% R
% Ser:
7
7
7
14
0
0
7
67
60
7
0
0
0
0
0
% S
% Thr:
0
7
0
0
0
20
0
0
0
7
7
7
0
0
80
% T
% Val:
0
0
0
54
7
7
7
0
7
0
47
7
0
80
7
% V
% Trp:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
7
7
0
0
7
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _