Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: IMPA1 All Species: 31.52
Human Site: S38 Identified Species: 49.52
UniProt: P29218 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P29218 NP_001138350.1 277 30189 S38 M N V M L K S S P V D L V T A
Chimpanzee Pan troglodytes XP_001168821 277 30156 S38 M N V M L K S S P V D L V T A
Rhesus Macaque Macaca mulatta XP_001092596 277 30251 S38 M N V M L K S S P V D L V T A
Dog Lupus familis XP_535114 277 30225 S38 M N V M I K S S P A D L V T A
Cat Felis silvestris
Mouse Mus musculus O55023 277 30418 S38 M D V M I K S S P A D L V T V
Rat Rattus norvegicus P97697 277 30493 S38 M D V M I K S S P A D L V T V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508686 235 25995 Y23 C I W F Y V N Y R F I A E E S
Chicken Gallus gallus XP_418310 278 30123 S38 K S I M I K S S P V D L V T E
Frog Xenopus laevis P29219 285 30711 A41 I M V K T S L A P A D L V T A
Zebra Danio Brachydanio rerio NP_001002745 282 30560 S38 L K I M C K S S S V D L V T K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_393191 272 29815 C37 K D A M T K S C E V D L V T E
Nematode Worm Caenorhab. elegans Q19420 285 30962 S44 S K V D T K S S N T D L V T E
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9M8S8 271 29103 G39 T K H V E H K G Q V D L V T E
Baker's Yeast Sacchar. cerevisiae Q05533 292 32074 A42 F C S Y D D K A N G V D L V T
Red Bread Mold Neurospora crassa P11634 340 37305 V63 K D S A V D I V T Q T D E D V
Conservation
Percent
Protein Identity: 100 99.6 97.8 90.2 N.A. 86.2 84.8 N.A. 46.5 82 74.3 65.9 N.A. N.A. 49 45.6 N.A.
Protein Similarity: 100 100 99.6 95.6 N.A. 94.2 93.8 N.A. 64.2 92.8 88.7 82.6 N.A. N.A. 67.1 60.3 N.A.
P-Site Identity: 100 100 100 86.6 N.A. 73.3 73.3 N.A. 0 66.6 46.6 60 N.A. N.A. 53.3 53.3 N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 86.6 86.6 N.A. 13.3 86.6 60 73.3 N.A. N.A. 60 53.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 40.7 36.3 30.5
Protein Similarity: N.A. N.A. N.A. 61 55.1 46.4
P-Site Identity: N.A. N.A. N.A. 33.3 0 0
P-Site Similarity: N.A. N.A. N.A. 40 13.3 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 7 7 0 0 0 14 0 27 0 7 0 0 34 % A
% Cys: 7 7 0 0 7 0 0 7 0 0 0 0 0 0 0 % C
% Asp: 0 27 0 7 7 14 0 0 0 0 80 14 0 7 0 % D
% Glu: 0 0 0 0 7 0 0 0 7 0 0 0 14 7 27 % E
% Phe: 7 0 0 7 0 0 0 0 0 7 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 7 0 7 0 0 0 0 0 % G
% His: 0 0 7 0 0 7 0 0 0 0 0 0 0 0 0 % H
% Ile: 7 7 14 0 27 0 7 0 0 0 7 0 0 0 0 % I
% Lys: 20 20 0 7 0 67 14 0 0 0 0 0 0 0 7 % K
% Leu: 7 0 0 0 20 0 7 0 0 0 0 80 7 0 0 % L
% Met: 40 7 0 60 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 27 0 0 0 0 7 0 14 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 54 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 7 7 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % R
% Ser: 7 7 14 0 0 7 67 60 7 0 0 0 0 0 7 % S
% Thr: 7 0 0 0 20 0 0 0 7 7 7 0 0 80 7 % T
% Val: 0 0 54 7 7 7 0 7 0 47 7 0 80 7 20 % V
% Trp: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 7 7 0 0 7 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _