KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IMPA1
All Species:
9.09
Human Site:
T168
Identified Species:
14.29
UniProt:
P29218
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P29218
NP_001138350.1
277
30189
T168
T
E
L
G
S
S
R
T
P
E
T
V
R
M
V
Chimpanzee
Pan troglodytes
XP_001168821
277
30156
T168
T
E
L
G
S
S
R
T
P
E
T
V
R
M
V
Rhesus Macaque
Macaca mulatta
XP_001092596
277
30251
T168
T
E
L
G
S
S
R
T
P
E
T
V
R
I
V
Dog
Lupus familis
XP_535114
277
30225
A168
T
E
F
G
S
S
R
A
P
E
T
V
R
I
V
Cat
Felis silvestris
Mouse
Mus musculus
O55023
277
30418
K168
T
E
L
G
S
S
R
K
P
E
T
L
R
I
V
Rat
Rattus norvegicus
P97697
277
30493
K168
T
E
L
G
S
S
R
K
P
E
T
L
R
I
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508686
235
25995
I151
K
A
H
G
V
R
V
I
G
S
S
T
L
A
L
Chicken
Gallus gallus
XP_418310
278
30123
D168
T
E
L
G
S
N
R
D
P
E
T
I
K
I
V
Frog
Xenopus laevis
P29219
285
30711
P172
E
L
G
S
N
R
N
P
E
F
I
K
T
V
S
Zebra Danio
Brachydanio rerio
NP_001002745
282
30560
D168
T
E
F
G
S
N
R
D
P
E
N
V
E
K
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393191
272
29815
R166
M
M
E
M
G
T
S
R
D
P
E
K
M
K
I
Nematode Worm
Caenorhab. elegans
Q19420
285
30962
G178
L
H
N
R
V
Q
F
G
D
R
W
L
D
I
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M8S8
271
29103
D169
T
E
A
G
T
K
R
D
K
A
T
L
D
D
T
Baker's Yeast
Sacchar. cerevisiae
Q05533
292
32074
N179
R
T
E
G
S
Q
G
N
F
D
K
K
M
N
T
Red Bread Mold
Neurospora crassa
P11634
340
37305
E210
G
N
L
Y
R
K
V
E
S
F
V
N
M
A
A
Conservation
Percent
Protein Identity:
100
99.6
97.8
90.2
N.A.
86.2
84.8
N.A.
46.5
82
74.3
65.9
N.A.
N.A.
49
45.6
N.A.
Protein Similarity:
100
100
99.6
95.6
N.A.
94.2
93.8
N.A.
64.2
92.8
88.7
82.6
N.A.
N.A.
67.1
60.3
N.A.
P-Site Identity:
100
100
93.3
80
N.A.
80
80
N.A.
6.6
66.6
0
53.3
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
100
100
100
86.6
N.A.
93.3
93.3
N.A.
20
93.3
13.3
66.6
N.A.
N.A.
13.3
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
40.7
36.3
30.5
Protein Similarity:
N.A.
N.A.
N.A.
61
55.1
46.4
P-Site Identity:
N.A.
N.A.
N.A.
33.3
13.3
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
20
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
7
0
0
0
0
7
0
7
0
0
0
14
14
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
20
14
7
0
0
14
7
0
% D
% Glu:
7
60
14
0
0
0
0
7
7
54
7
0
7
0
0
% E
% Phe:
0
0
14
0
0
0
7
0
7
14
0
0
0
0
0
% F
% Gly:
7
0
7
74
7
0
7
7
7
0
0
0
0
0
0
% G
% His:
0
7
7
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
7
0
0
7
7
0
40
14
% I
% Lys:
7
0
0
0
0
14
0
14
7
0
7
20
7
14
0
% K
% Leu:
7
7
47
0
0
0
0
0
0
0
0
27
7
0
7
% L
% Met:
7
7
0
7
0
0
0
0
0
0
0
0
20
14
0
% M
% Asn:
0
7
7
0
7
14
7
7
0
0
7
7
0
7
0
% N
% Pro:
0
0
0
0
0
0
0
7
54
7
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
14
0
0
0
0
0
0
0
0
0
% Q
% Arg:
7
0
0
7
7
14
60
7
0
7
0
0
40
0
0
% R
% Ser:
0
0
0
7
60
40
7
0
7
7
7
0
0
0
7
% S
% Thr:
60
7
0
0
7
7
0
20
0
0
54
7
7
0
14
% T
% Val:
0
0
0
0
14
0
14
0
0
0
7
34
0
7
47
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% W
% Tyr:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _