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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IMPA1
All Species:
31.21
Human Site:
Y11
Identified Species:
49.05
UniProt:
P29218
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P29218
NP_001138350.1
277
30189
Y11
P
W
Q
E
C
M
D
Y
A
V
T
L
A
R
Q
Chimpanzee
Pan troglodytes
XP_001168821
277
30156
Y11
P
W
Q
E
C
M
D
Y
A
V
T
L
A
R
Q
Rhesus Macaque
Macaca mulatta
XP_001092596
277
30251
Y11
P
W
Q
E
C
M
D
Y
A
V
T
L
A
R
R
Dog
Lupus familis
XP_535114
277
30225
Y11
P
W
Q
E
C
M
D
Y
A
V
T
L
A
R
Q
Cat
Felis silvestris
Mouse
Mus musculus
O55023
277
30418
Y11
P
W
Q
E
C
M
D
Y
A
V
I
L
A
R
Q
Rat
Rattus norvegicus
P97697
277
30493
Y11
P
W
Q
E
C
M
D
Y
A
V
I
L
A
R
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508686
235
25995
Chicken
Gallus gallus
XP_418310
278
30123
Y11
P
W
Q
E
C
M
D
Y
A
V
T
L
A
K
K
Frog
Xenopus laevis
P29219
285
30711
L12
W
Q
E
C
M
D
F
L
A
V
S
I
A
R
K
Zebra Danio
Brachydanio rerio
NP_001002745
282
30560
H11
L
W
Q
D
A
M
D
H
A
V
T
L
A
R
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393191
272
29815
V10
N
T
D
K
Y
Y
T
V
V
L
R
L
V
L
E
Nematode Worm
Caenorhab. elegans
Q19420
285
30962
Y16
E
E
Q
V
F
V
D
Y
A
I
E
L
V
K
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M8S8
271
29103
A13
S
L
D
Q
F
L
A
A
A
I
D
A
A
K
K
Baker's Yeast
Sacchar. cerevisiae
Q05533
292
32074
T14
V
L
E
E
V
E
N
T
F
I
E
L
L
R
S
Red Bread Mold
Neurospora crassa
P11634
340
37305
F17
E
L
D
E
I
Y
T
F
A
V
Q
L
G
K
D
Conservation
Percent
Protein Identity:
100
99.6
97.8
90.2
N.A.
86.2
84.8
N.A.
46.5
82
74.3
65.9
N.A.
N.A.
49
45.6
N.A.
Protein Similarity:
100
100
99.6
95.6
N.A.
94.2
93.8
N.A.
64.2
92.8
88.7
82.6
N.A.
N.A.
67.1
60.3
N.A.
P-Site Identity:
100
100
93.3
100
N.A.
93.3
93.3
N.A.
0
86.6
26.6
66.6
N.A.
N.A.
6.6
33.3
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
0
100
53.3
86.6
N.A.
N.A.
26.6
60
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
40.7
36.3
30.5
Protein Similarity:
N.A.
N.A.
N.A.
61
55.1
46.4
P-Site Identity:
N.A.
N.A.
N.A.
13.3
20
26.6
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
40
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
7
0
7
7
80
0
0
7
67
0
0
% A
% Cys:
0
0
0
7
47
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
20
7
0
7
60
0
0
0
7
0
0
0
7
% D
% Glu:
14
7
14
60
0
7
0
0
0
0
14
0
0
0
7
% E
% Phe:
0
0
0
0
14
0
7
7
7
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% G
% His:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
7
0
0
0
0
20
14
7
0
0
0
% I
% Lys:
0
0
0
7
0
0
0
0
0
0
0
0
0
27
34
% K
% Leu:
7
20
0
0
0
7
0
7
0
7
0
80
7
7
0
% L
% Met:
0
0
0
0
7
54
0
0
0
0
0
0
0
0
0
% M
% Asn:
7
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% N
% Pro:
47
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
7
60
7
0
0
0
0
0
0
7
0
0
0
34
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
7
0
0
60
7
% R
% Ser:
7
0
0
0
0
0
0
0
0
0
7
0
0
0
7
% S
% Thr:
0
7
0
0
0
0
14
7
0
0
40
0
0
0
0
% T
% Val:
7
0
0
7
7
7
0
7
7
67
0
0
14
0
0
% V
% Trp:
7
54
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
7
14
0
54
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _