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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADORA2A
All Species:
13.33
Human Site:
S350
Identified Species:
36.67
UniProt:
P29274
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P29274
NP_000666.2
412
44707
S350
P
G
V
W
A
N
G
S
A
P
H
P
E
R
R
Chimpanzee
Pan troglodytes
XP_515035
412
44761
S350
P
G
V
W
A
N
G
S
A
P
H
P
E
R
R
Rhesus Macaque
Macaca mulatta
Q28509
415
46453
N361
Y
S
S
N
S
N
G
N
T
G
E
Q
S
G
Y
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q60613
410
44864
S345
L
G
V
W
A
N
G
S
A
P
H
S
G
R
R
Rat
Rattus norvegicus
P30543
410
44980
S345
L
G
V
W
A
N
G
S
A
T
H
S
G
R
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506602
343
37885
D292
R
S
N
G
N
G
L
D
L
E
T
N
G
Q
V
Chicken
Gallus gallus
O13076
340
37753
I289
N
S
V
I
N
P
I
I
Y
A
Y
R
I
R
D
Frog
Xenopus laevis
O42574
385
43291
Y325
S
A
F
N
P
I
I
Y
C
R
S
P
D
F
R
Zebra Danio
Brachydanio rerio
NP_001034904
442
49092
T349
L
Y
A
E
Q
S
S
T
T
S
S
C
E
S
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
24.1
N.A.
N.A.
79.8
80.5
N.A.
49
51.9
27.9
58.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
41.6
N.A.
N.A.
84.9
85.6
N.A.
58.5
64
44.9
69.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
13.3
N.A.
N.A.
80
73.3
N.A.
0
13.3
13.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
26.6
N.A.
N.A.
80
73.3
N.A.
6.6
20
20
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
12
0
45
0
0
0
45
12
0
0
0
0
12
% A
% Cys:
0
0
0
0
0
0
0
0
12
0
0
12
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
12
0
0
0
0
12
0
12
% D
% Glu:
0
0
0
12
0
0
0
0
0
12
12
0
34
0
0
% E
% Phe:
0
0
12
0
0
0
0
0
0
0
0
0
0
12
0
% F
% Gly:
0
45
0
12
0
12
56
0
0
12
0
0
34
12
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
45
0
0
0
0
% H
% Ile:
0
0
0
12
0
12
23
12
0
0
0
0
12
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
34
0
0
0
0
0
12
0
12
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
12
0
12
23
23
56
0
12
0
0
0
12
0
0
0
% N
% Pro:
23
0
0
0
12
12
0
0
0
34
0
34
0
0
0
% P
% Gln:
0
0
0
0
12
0
0
0
0
0
0
12
0
12
0
% Q
% Arg:
12
0
0
0
0
0
0
0
0
12
0
12
0
56
56
% R
% Ser:
12
34
12
0
12
12
12
45
0
12
23
23
12
12
0
% S
% Thr:
0
0
0
0
0
0
0
12
23
12
12
0
0
0
0
% T
% Val:
0
0
56
0
0
0
0
0
0
0
0
0
0
0
12
% V
% Trp:
0
0
0
45
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
12
12
0
0
0
0
0
12
12
0
12
0
0
0
12
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _