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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADORA2B
All Species:
6.97
Human Site:
S317
Identified Species:
17.04
UniProt:
P29275
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P29275
NP_000667.1
332
36333
S317
L
C
Q
A
D
V
K
S
G
N
G
Q
A
G
V
Chimpanzee
Pan troglodytes
XP_511779
332
36319
S317
L
C
Q
A
D
V
K
S
G
N
G
Q
A
G
V
Rhesus Macaque
Macaca mulatta
Q28524
418
44639
A373
R
L
P
R
E
P
C
A
A
D
R
P
A
S
S
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q60614
332
36046
G317
L
C
Q
A
E
T
K
G
G
S
G
Q
A
G
A
Rat
Rattus norvegicus
P29276
332
36349
G317
L
C
Q
T
D
T
K
G
G
S
G
Q
A
G
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509345
771
83686
P749
L
C
R
K
D
E
F
P
K
G
S
N
G
H
S
Chicken
Gallus gallus
O13076
340
37753
K317
C
K
T
D
D
F
P
K
C
T
T
D
N
N
Q
Frog
Xenopus laevis
O42574
385
43291
T351
K
A
D
R
H
L
H
T
T
G
E
L
S
R
Y
Zebra Danio
Brachydanio rerio
NP_001034902
351
39480
Y330
L
C
Q
R
D
E
L
Y
R
S
S
N
G
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783114
400
44682
Q318
L
C
G
I
I
Q
V
Q
N
C
D
S
G
D
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
28.7
N.A.
N.A.
87
86.1
N.A.
26.2
64.7
27
59.5
N.A.
N.A.
N.A.
N.A.
38
Protein Similarity:
100
99.6
42.8
N.A.
N.A.
92.7
92.1
N.A.
33.7
76.4
45.7
73.7
N.A.
N.A.
N.A.
N.A.
54.2
P-Site Identity:
100
100
6.6
N.A.
N.A.
66.6
66.6
N.A.
20
6.6
0
26.6
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
26.6
N.A.
N.A.
80
73.3
N.A.
26.6
6.6
20
33.3
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
30
0
0
0
10
10
0
0
0
50
0
10
% A
% Cys:
10
70
0
0
0
0
10
0
10
10
0
0
0
0
0
% C
% Asp:
0
0
10
10
60
0
0
0
0
10
10
10
0
10
10
% D
% Glu:
0
0
0
0
20
20
0
0
0
0
10
0
0
0
0
% E
% Phe:
0
0
0
0
0
10
10
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
10
0
0
0
0
20
40
20
40
0
30
40
10
% G
% His:
0
0
0
0
10
0
10
0
0
0
0
0
0
10
0
% H
% Ile:
0
0
0
10
10
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
10
10
0
10
0
0
40
10
10
0
0
0
0
0
0
% K
% Leu:
70
10
0
0
0
10
10
0
0
0
0
10
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
10
20
0
20
10
10
0
% N
% Pro:
0
0
10
0
0
10
10
10
0
0
0
10
0
0
0
% P
% Gln:
0
0
50
0
0
10
0
10
0
0
0
40
0
0
10
% Q
% Arg:
10
0
10
30
0
0
0
0
10
0
10
0
0
10
0
% R
% Ser:
0
0
0
0
0
0
0
20
0
30
20
10
10
20
30
% S
% Thr:
0
0
10
10
0
20
0
10
10
10
10
0
0
0
0
% T
% Val:
0
0
0
0
0
20
10
0
0
0
0
0
0
0
20
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _