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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADORA2B
All Species:
17.88
Human Site:
T225
Identified Species:
43.7
UniProt:
P29275
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P29275
NP_000667.1
332
36333
T225
L
M
D
H
S
R
T
T
L
Q
R
E
I
H
A
Chimpanzee
Pan troglodytes
XP_511779
332
36319
T225
L
M
D
H
S
R
T
T
L
Q
R
E
I
H
A
Rhesus Macaque
Macaca mulatta
Q28524
418
44639
L283
C
R
R
P
A
R
L
L
P
L
R
E
H
R
A
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q60614
332
36046
T225
L
M
D
H
S
R
T
T
L
Q
R
E
I
H
A
Rat
Rattus norvegicus
P29276
332
36349
T225
L
M
E
H
S
R
T
T
L
Q
R
E
I
H
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509345
771
83686
I660
L
M
D
N
S
R
T
I
L
Q
R
E
V
N
A
Chicken
Gallus gallus
O13076
340
37753
T225
L
M
G
N
S
R
T
T
L
Q
K
E
V
H
A
Frog
Xenopus laevis
O42574
385
43291
L263
R
R
I
L
S
K
I
L
V
A
K
E
Q
K
A
Zebra Danio
Brachydanio rerio
NP_001034902
351
39480
L240
G
E
N
Q
H
H
G
L
L
Q
R
E
I
R
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783114
400
44682
G235
S
R
L
A
V
K
E
G
N
A
A
K
L
L
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
28.7
N.A.
N.A.
87
86.1
N.A.
26.2
64.7
27
59.5
N.A.
N.A.
N.A.
N.A.
38
Protein Similarity:
100
99.6
42.8
N.A.
N.A.
92.7
92.1
N.A.
33.7
76.4
45.7
73.7
N.A.
N.A.
N.A.
N.A.
54.2
P-Site Identity:
100
100
26.6
N.A.
N.A.
100
93.3
N.A.
73.3
73.3
20
40
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
33.3
N.A.
N.A.
100
100
N.A.
93.3
93.3
40
46.6
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
10
0
0
0
0
20
10
0
0
0
100
% A
% Cys:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
40
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
10
10
0
0
0
10
0
0
0
0
90
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
10
0
0
0
10
10
0
0
0
0
0
0
0
% G
% His:
0
0
0
40
10
10
0
0
0
0
0
0
10
50
0
% H
% Ile:
0
0
10
0
0
0
10
10
0
0
0
0
50
0
0
% I
% Lys:
0
0
0
0
0
20
0
0
0
0
20
10
0
10
0
% K
% Leu:
60
0
10
10
0
0
10
30
70
10
0
0
10
10
0
% L
% Met:
0
60
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
20
0
0
0
0
10
0
0
0
0
10
0
% N
% Pro:
0
0
0
10
0
0
0
0
10
0
0
0
0
0
0
% P
% Gln:
0
0
0
10
0
0
0
0
0
70
0
0
10
0
0
% Q
% Arg:
10
30
10
0
0
70
0
0
0
0
70
0
0
20
0
% R
% Ser:
10
0
0
0
70
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
60
50
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
10
0
0
0
10
0
0
0
20
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _