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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CTGF
All Species:
31.21
Human Site:
S275
Identified Species:
76.3
UniProt:
P29279
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P29279
NP_001892.1
349
38091
S275
F
E
L
S
G
C
T
S
M
K
T
Y
R
A
K
Chimpanzee
Pan troglodytes
A5A6L1
381
41994
S305
F
T
Y
A
G
C
L
S
V
K
K
Y
R
P
K
Rhesus Macaque
Macaca mulatta
XP_001104316
327
35611
S253
F
E
L
S
G
C
T
S
V
K
T
Y
R
A
K
Dog
Lupus familis
XP_533406
305
33547
F239
V
K
T
Y
R
A
K
F
C
G
V
C
T
D
G
Cat
Felis silvestris
Mouse
Mus musculus
P29268
348
37775
S274
F
E
L
S
G
C
T
S
V
K
T
Y
R
A
K
Rat
Rattus norvegicus
Q9R1E9
347
37737
S273
F
E
L
S
G
C
T
S
V
K
T
Y
R
A
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506042
624
68066
S550
F
E
L
S
G
C
T
S
V
K
S
Y
K
A
K
Chicken
Gallus gallus
P28686
351
38250
S277
F
E
Y
K
N
C
T
S
V
Q
T
Y
K
P
R
Frog
Xenopus laevis
P51609
343
38052
S268
F
H
Y
K
N
C
T
S
V
Q
P
Y
K
P
K
Zebra Danio
Brachydanio rerio
NP_001015041
345
38360
T271
F
E
I
S
G
C
T
T
T
K
S
Y
R
P
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
46.4
83.9
75.6
N.A.
90.8
91.4
N.A.
50.6
52.9
51.5
77.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
62.9
86.5
79.6
N.A.
95.4
95.6
N.A.
53.8
67.5
67.6
87.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
53.3
93.3
0
N.A.
93.3
93.3
N.A.
80
46.6
40
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
66.6
100
6.6
N.A.
100
100
N.A.
100
73.3
60
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
10
0
0
0
0
0
0
0
50
0
% A
% Cys:
0
0
0
0
0
90
0
0
10
0
0
10
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% D
% Glu:
0
70
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
90
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
70
0
0
0
0
10
0
0
0
0
10
% G
% His:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
10
0
20
0
0
10
0
0
70
10
0
30
0
80
% K
% Leu:
0
0
50
0
0
0
10
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
20
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
10
0
0
40
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
20
0
0
0
0
0
% Q
% Arg:
0
0
0
0
10
0
0
0
0
0
0
0
60
0
10
% R
% Ser:
0
0
0
60
0
0
0
80
0
0
20
0
0
0
0
% S
% Thr:
0
10
10
0
0
0
80
10
10
0
50
0
10
0
0
% T
% Val:
10
0
0
0
0
0
0
0
70
0
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
30
10
0
0
0
0
0
0
0
90
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _