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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPHA8
All Species:
12.42
Human Site:
S643
Identified Species:
30.37
UniProt:
P29322
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P29322
NP_065387.1
1005
111003
S643
H
I
E
K
I
I
G
S
G
D
S
G
E
V
C
Chimpanzee
Pan troglodytes
P0C0K6
1020
110674
T677
K
I
E
E
V
I
G
T
G
S
F
G
E
V
R
Rhesus Macaque
Macaca mulatta
XP_001101560
1005
110887
S643
H
I
E
K
I
I
G
S
G
E
S
G
E
V
C
Dog
Lupus familis
XP_544509
1216
132649
V859
G
S
G
E
S
G
E
V
C
Y
G
R
L
R
V
Cat
Felis silvestris
Mouse
Mus musculus
O09127
1004
110746
S642
H
I
E
K
I
I
G
S
G
E
S
G
E
V
C
Rat
Rattus norvegicus
P54759
998
111935
A641
K
I
E
R
V
I
G
A
G
E
F
G
E
V
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510807
979
108960
A625
T
I
E
R
V
I
G
A
G
E
F
G
E
V
C
Chicken
Gallus gallus
O42422
993
111348
A636
K
I
E
R
V
I
G
A
G
E
F
G
E
V
C
Frog
Xenopus laevis
Q91694
985
109711
E633
I
G
V
G
E
F
G
E
V
C
S
G
R
L
K
Zebra Danio
Brachydanio rerio
O13146
981
109636
A634
R
I
E
R
V
I
G
A
G
E
F
G
E
V
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
41.2
99.3
73.8
N.A.
95.1
56.1
N.A.
57.3
56.9
56
56.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
60.8
99.5
75.4
N.A.
97.1
72.8
N.A.
73.3
73
71.3
70.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
53.3
93.3
0
N.A.
93.3
60
N.A.
60
60
20
60
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
73.3
100
6.6
N.A.
100
86.6
N.A.
86.6
86.6
26.6
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
40
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
10
10
0
0
0
0
70
% C
% Asp:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% D
% Glu:
0
0
80
20
10
0
10
10
0
60
0
0
80
0
0
% E
% Phe:
0
0
0
0
0
10
0
0
0
0
50
0
0
0
0
% F
% Gly:
10
10
10
10
0
10
90
0
80
0
10
90
0
0
0
% G
% His:
30
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
80
0
0
30
80
0
0
0
0
0
0
0
0
0
% I
% Lys:
30
0
0
30
0
0
0
0
0
0
0
0
0
0
10
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
10
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
10
0
0
40
0
0
0
0
0
0
0
10
10
10
10
% R
% Ser:
0
10
0
0
10
0
0
30
0
10
40
0
0
0
0
% S
% Thr:
10
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% T
% Val:
0
0
10
0
50
0
0
10
10
0
0
0
0
80
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _