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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MPG All Species: 16.36
Human Site: Y75 Identified Species: 40
UniProt: P29372 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P29372 NP_001015052.1 298 32869 Y75 P G P Y R S I Y F S S P K G H
Chimpanzee Pan troglodytes XP_001171583 413 45796 H108 D T D H G L W H H R A S W A E
Rhesus Macaque Macaca mulatta XP_001118427 538 58759 Y315 L G P Y R S I Y F S S P K G H
Dog Lupus familis XP_854372 499 51978 Y276 L G P R R S I Y F S S P K S H
Cat Felis silvestris
Mouse Mus musculus Q04841 333 36469 Y95 P G L R R S I Y F S S P E D H
Rat Rattus norvegicus P23571 317 34784 Y81 P G L L R S I Y F S S P E D R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_414945 273 30255 F59 S S Q L E A D F F N Q P C I S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001076319 282 31681 T60 M R D S P R L T Y S F F N Q P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001119913 330 38095 T103 Q L E D P P L T V W E K E I C
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786488 305 33526 L81 I P A A Q S Q L A D K M P S A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 55.6 51.2 47.9 N.A. 64.2 65.3 N.A. N.A. 49.6 N.A. 51.3 N.A. N.A. 35.4 N.A. 39.3
Protein Similarity: 100 61.2 53.3 52 N.A. 70.5 72.8 N.A. N.A. 68.4 N.A. 63.7 N.A. N.A. 52.7 N.A. 54.7
P-Site Identity: 100 0 93.3 80 N.A. 73.3 66.6 N.A. N.A. 13.3 N.A. 6.6 N.A. N.A. 0 N.A. 6.6
P-Site Similarity: 100 20 93.3 80 N.A. 80 73.3 N.A. N.A. 33.3 N.A. 20 N.A. N.A. 13.3 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 10 0 10 0 0 10 0 10 0 0 10 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 10 % C
% Asp: 10 0 20 10 0 0 10 0 0 10 0 0 0 20 0 % D
% Glu: 0 0 10 0 10 0 0 0 0 0 10 0 30 0 10 % E
% Phe: 0 0 0 0 0 0 0 10 60 0 10 10 0 0 0 % F
% Gly: 0 50 0 0 10 0 0 0 0 0 0 0 0 20 0 % G
% His: 0 0 0 10 0 0 0 10 10 0 0 0 0 0 40 % H
% Ile: 10 0 0 0 0 0 50 0 0 0 0 0 0 20 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 10 10 30 0 0 % K
% Leu: 20 10 20 20 0 10 20 10 0 0 0 0 0 0 0 % L
% Met: 10 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 10 0 0 10 0 0 % N
% Pro: 30 10 30 0 20 10 0 0 0 0 0 60 10 0 10 % P
% Gln: 10 0 10 0 10 0 10 0 0 0 10 0 0 10 0 % Q
% Arg: 0 10 0 20 50 10 0 0 0 10 0 0 0 0 10 % R
% Ser: 10 10 0 10 0 60 0 0 0 60 50 10 0 20 10 % S
% Thr: 0 10 0 0 0 0 0 20 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 10 0 0 10 0 0 10 0 0 % W
% Tyr: 0 0 0 20 0 0 0 50 10 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _