KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TKT
All Species:
40.3
Human Site:
S595
Identified Species:
68.21
UniProt:
P29401
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P29401
NP_001055.1
623
67878
S595
A
V
N
R
V
P
R
S
G
K
P
A
E
L
L
Chimpanzee
Pan troglodytes
Q5R1W6
623
67821
S595
A
V
N
R
V
P
R
S
G
K
P
A
E
L
L
Rhesus Macaque
Macaca mulatta
XP_001095403
703
76522
H676
A
V
S
G
V
P
Q
H
G
K
T
S
E
L
L
Dog
Lupus familis
XP_533792
619
67627
S591
A
V
G
E
V
P
R
S
G
K
P
A
E
L
L
Cat
Felis silvestris
Mouse
Mus musculus
P40142
623
67612
S595
A
V
S
Q
V
P
R
S
G
K
P
A
E
L
L
Rat
Rattus norvegicus
P50137
623
67625
S595
A
V
S
Q
V
P
R
S
G
K
P
A
E
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508404
725
77819
S697
A
V
A
H
I
P
R
S
G
K
P
V
E
L
L
Chicken
Gallus gallus
XP_414333
627
68436
S595
A
V
S
H
V
P
R
S
G
K
S
A
E
L
L
Frog
Xenopus laevis
NP_001083312
627
67992
S595
A
V
S
H
V
P
R
S
G
K
P
T
E
L
L
Zebra Danio
Brachydanio rerio
XP_685690
628
69366
S596
A
V
A
Q
V
P
R
S
G
K
M
N
D
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623357
627
67899
S600
A
I
P
E
V
P
R
S
G
P
P
T
A
L
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001177524
625
66606
S599
A
V
D
R
V
P
R
S
G
P
S
K
V
L
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q7SIC9
675
72975
A650
I
G
I
D
K
F
G
A
S
A
P
A
G
T
I
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P23254
680
73787
T663
V
A
E
R
A
Q
K
T
I
A
F
Y
K
G
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
61.1
87.3
N.A.
94.6
94
N.A.
74.6
84.2
78.3
71
N.A.
N.A.
62.2
N.A.
61.1
Protein Similarity:
100
99.6
72.2
91.8
N.A.
97.9
97.7
N.A.
81.2
92.3
90.4
84.5
N.A.
N.A.
76.2
N.A.
76.3
P-Site Identity:
100
100
60
86.6
N.A.
86.6
86.6
N.A.
73.3
80
80
66.6
N.A.
N.A.
60
N.A.
60
P-Site Similarity:
100
100
80
86.6
N.A.
100
100
N.A.
80
86.6
86.6
80
N.A.
N.A.
66.6
N.A.
73.3
Percent
Protein Identity:
N.A.
25.3
N.A.
N.A.
25.4
N.A.
Protein Similarity:
N.A.
42.3
N.A.
N.A.
41.1
N.A.
P-Site Identity:
N.A.
13.3
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
26.6
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
86
8
15
0
8
0
0
8
0
15
0
50
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
8
0
0
0
0
0
0
0
0
8
0
8
% D
% Glu:
0
0
8
15
0
0
0
0
0
0
0
0
65
0
0
% E
% Phe:
0
0
0
0
0
8
0
0
0
0
8
0
0
0
0
% F
% Gly:
0
8
8
8
0
0
8
0
86
0
0
0
8
8
0
% G
% His:
0
0
0
22
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
8
8
8
0
8
0
0
0
8
0
0
0
0
0
15
% I
% Lys:
0
0
0
0
8
0
8
0
0
72
0
8
8
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
86
79
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
15
0
0
0
0
0
0
0
0
8
0
0
0
% N
% Pro:
0
0
8
0
0
86
0
0
0
15
65
0
0
0
0
% P
% Gln:
0
0
0
22
0
8
8
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
29
0
0
79
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
36
0
0
0
0
79
8
0
15
8
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
8
0
0
8
15
0
8
0
% T
% Val:
8
79
0
0
79
0
0
0
0
0
0
8
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _