KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IL12A
All Species:
18.18
Human Site:
Y189
Identified Species:
50
UniProt:
P29459
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P29459
NP_000873.2
219
24874
Y189
S
L
E
E
P
D
F
Y
K
T
K
I
K
L
C
Chimpanzee
Pan troglodytes
XP_001156599
250
27947
Y220
S
L
E
E
L
D
F
Y
K
T
K
I
K
L
C
Rhesus Macaque
Macaca mulatta
P48091
219
24886
Y189
S
L
E
E
P
D
F
Y
K
T
K
I
K
L
C
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P43431
215
24161
Y185
P
V
G
E
A
D
P
Y
R
V
K
M
K
L
C
Rat
Rattus norvegicus
Q9R103
215
24228
Y185
P
M
G
E
A
D
P
Y
R
V
K
M
K
L
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516237
411
44728
Y381
S
Y
R
T
D
D
F
Y
K
T
K
I
K
L
C
Chicken
Gallus gallus
NP_998753
205
21926
F171
P
S
T
T
L
G
S
F
Q
G
R
M
R
L
C
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001343684
195
21830
R168
H
Q
K
S
F
Q
E
R
L
K
L
C
K
I
L
Tiger Blowfish
Takifugu rubipres
NP_001072066
196
21618
L169
R
L
K
L
C
K
V
L
R
G
F
Q
V
R
S
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.5
94
N.A.
N.A.
58.9
58.9
N.A.
27
26.9
N.A.
23.2
23.7
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
85.5
95.4
N.A.
N.A.
73.5
75.3
N.A.
36.9
44.7
N.A.
42.9
43.8
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
100
N.A.
N.A.
46.6
46.6
N.A.
73.3
13.3
N.A.
6.6
6.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
100
N.A.
N.A.
66.6
66.6
N.A.
73.3
46.6
N.A.
20
20
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
23
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
12
0
0
0
0
0
0
12
0
0
78
% C
% Asp:
0
0
0
0
12
67
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
34
56
0
0
12
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
12
0
45
12
0
0
12
0
0
0
0
% F
% Gly:
0
0
23
0
0
12
0
0
0
23
0
0
0
0
0
% G
% His:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
45
0
12
0
% I
% Lys:
0
0
23
0
0
12
0
0
45
12
67
0
78
0
0
% K
% Leu:
0
45
0
12
23
0
0
12
12
0
12
0
0
78
12
% L
% Met:
0
12
0
0
0
0
0
0
0
0
0
34
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
34
0
0
0
23
0
23
0
0
0
0
0
0
0
0
% P
% Gln:
0
12
0
0
0
12
0
0
12
0
0
12
0
0
0
% Q
% Arg:
12
0
12
0
0
0
0
12
34
0
12
0
12
12
0
% R
% Ser:
45
12
0
12
0
0
12
0
0
0
0
0
0
0
12
% S
% Thr:
0
0
12
23
0
0
0
0
0
45
0
0
0
0
0
% T
% Val:
0
12
0
0
0
0
12
0
0
23
0
0
12
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
12
0
0
0
0
0
67
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _