KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IL12B
All Species:
11.82
Human Site:
T294
Identified Species:
32.5
UniProt:
P29460
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P29460
NP_002178.2
328
37169
T294
D
R
V
F
T
D
K
T
S
A
T
V
I
C
R
Chimpanzee
Pan troglodytes
XP_527101
328
37111
T294
D
R
V
F
T
D
K
T
S
A
T
V
I
C
R
Rhesus Macaque
Macaca mulatta
P48095
328
37255
T294
D
R
I
F
T
D
K
T
S
A
T
V
I
C
R
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P43432
335
38217
K291
T
E
E
G
C
N
Q
K
G
A
F
L
V
E
K
Rat
Rattus norvegicus
NP_072133
335
38395
K291
T
E
E
E
C
N
Q
K
G
A
F
L
V
E
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506487
369
41956
T317
H
I
L
M
A
D
G
T
S
V
K
V
K
C
H
Chicken
Gallus gallus
NP_998736
315
36130
S282
V
Y
D
A
D
E
Q
S
I
Q
I
P
K
T
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001007109
324
37297
C290
V
S
K
G
K
M
V
C
V
R
A
K
D
E
F
Tiger Blowfish
Takifugu rubipres
NP_001094074
359
40439
V303
H
P
C
T
Q
T
R
V
T
K
T
L
T
V
S
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
96.3
N.A.
N.A.
67.4
67.1
N.A.
56.6
45.4
N.A.
29.2
27.8
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.3
98.4
N.A.
N.A.
79.4
80.3
N.A.
67.4
65.2
N.A.
47.8
51.5
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
N.A.
N.A.
6.6
6.6
N.A.
33.3
0
N.A.
0
6.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
N.A.
N.A.
40
40
N.A.
40
20
N.A.
0
26.6
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
12
12
0
0
0
0
56
12
0
0
0
0
% A
% Cys:
0
0
12
0
23
0
0
12
0
0
0
0
0
45
0
% C
% Asp:
34
0
12
0
12
45
0
0
0
0
0
0
12
0
0
% D
% Glu:
0
23
23
12
0
12
0
0
0
0
0
0
0
34
0
% E
% Phe:
0
0
0
34
0
0
0
0
0
0
23
0
0
0
12
% F
% Gly:
0
0
0
23
0
0
12
0
23
0
0
0
0
0
12
% G
% His:
23
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% H
% Ile:
0
12
12
0
0
0
0
0
12
0
12
0
34
0
0
% I
% Lys:
0
0
12
0
12
0
34
23
0
12
12
12
23
0
23
% K
% Leu:
0
0
12
0
0
0
0
0
0
0
0
34
0
0
0
% L
% Met:
0
0
0
12
0
12
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
23
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
12
0
0
0
0
0
0
0
0
0
12
0
0
0
% P
% Gln:
0
0
0
0
12
0
34
0
0
12
0
0
0
0
0
% Q
% Arg:
0
34
0
0
0
0
12
0
0
12
0
0
0
0
34
% R
% Ser:
0
12
0
0
0
0
0
12
45
0
0
0
0
0
12
% S
% Thr:
23
0
0
12
34
12
0
45
12
0
45
0
12
12
0
% T
% Val:
23
0
23
0
0
0
12
12
12
12
0
45
23
12
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _