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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CASP1
All Species:
7.58
Human Site:
S110
Identified Species:
20.83
UniProt:
P29466
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P29466
NP_001214.1
404
45159
S110
D
S
Q
G
V
L
S
S
F
P
A
P
Q
A
V
Chimpanzee
Pan troglodytes
XP_001136115
404
45213
S110
D
S
Q
G
V
L
S
S
F
P
A
P
Q
A
V
Rhesus Macaque
Macaca mulatta
Q153Z0
421
47740
S125
K
D
E
E
R
A
A
S
A
H
S
M
A
V
P
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P29452
402
45622
P109
E
D
S
K
G
G
H
P
S
S
S
E
T
K
E
Rat
Rattus norvegicus
P43527
402
45557
P109
E
D
S
K
G
G
H
P
F
S
S
E
T
K
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509500
456
52101
A163
A
A
K
L
G
L
S
A
V
P
Q
A
L
Q
A
Chicken
Gallus gallus
Q98943
424
47941
E121
N
L
P
L
P
L
S
E
S
C
N
S
K
R
P
Frog
Xenopus laevis
P55865
386
43644
H101
A
P
V
P
I
Q
E
H
N
A
D
T
I
K
N
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P42573
503
56598
S110
E
C
P
M
S
P
A
S
H
R
R
S
R
A
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.7
42.9
N.A.
N.A.
61.6
62.1
N.A.
39.4
21.9
42
N.A.
N.A.
N.A.
N.A.
24.4
N.A.
Protein Similarity:
100
99.5
60.8
N.A.
N.A.
74.5
74
N.A.
57.2
42.4
58.4
N.A.
N.A.
N.A.
N.A.
41.3
N.A.
P-Site Identity:
100
100
6.6
N.A.
N.A.
0
6.6
N.A.
20
13.3
0
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
100
100
26.6
N.A.
N.A.
13.3
20
N.A.
40
26.6
6.6
N.A.
N.A.
N.A.
N.A.
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
23
12
0
0
0
12
23
12
12
12
23
12
12
34
12
% A
% Cys:
0
12
0
0
0
0
0
0
0
12
0
0
0
0
0
% C
% Asp:
23
34
0
0
0
0
0
0
0
0
12
0
0
0
0
% D
% Glu:
34
0
12
12
0
0
12
12
0
0
0
23
0
0
23
% E
% Phe:
0
0
0
0
0
0
0
0
34
0
0
0
0
0
0
% F
% Gly:
0
0
0
23
34
23
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
23
12
12
12
0
0
0
0
0
% H
% Ile:
0
0
0
0
12
0
0
0
0
0
0
0
12
0
0
% I
% Lys:
12
0
12
23
0
0
0
0
0
0
0
0
12
34
0
% K
% Leu:
0
12
0
23
0
45
0
0
0
0
0
0
12
0
12
% L
% Met:
0
0
0
12
0
0
0
0
0
0
0
12
0
0
0
% M
% Asn:
12
0
0
0
0
0
0
0
12
0
12
0
0
0
12
% N
% Pro:
0
12
23
12
12
12
0
23
0
34
0
23
0
0
23
% P
% Gln:
0
0
23
0
0
12
0
0
0
0
12
0
23
12
0
% Q
% Arg:
0
0
0
0
12
0
0
0
0
12
12
0
12
12
0
% R
% Ser:
0
23
23
0
12
0
45
45
23
23
34
23
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
12
23
0
0
% T
% Val:
0
0
12
0
23
0
0
0
12
0
0
0
0
12
23
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _