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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SERPINB3
All Species:
18.18
Human Site:
S149
Identified Species:
57.14
UniProt:
P29508
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P29508
NP_008850.1
390
44565
S149
E
S
R
K
K
I
N
S
W
V
E
S
Q
T
N
Chimpanzee
Pan troglodytes
XP_512165
390
44653
S149
E
S
R
K
K
I
N
S
W
V
E
S
Q
T
N
Rhesus Macaque
Macaca mulatta
XP_001091267
390
44690
S149
E
S
R
K
K
I
N
S
W
V
E
S
Q
T
N
Dog
Lupus familis
XP_541074
389
44529
S150
E
S
R
K
K
I
N
S
W
V
E
S
Q
T
N
Cat
Felis silvestris
Mouse
Mus musculus
Q8CDC0
389
44313
S149
E
S
R
K
K
I
N
S
W
V
E
S
Q
T
N
Rat
Rattus norvegicus
Q4G075
379
42708
L148
E
G
K
I
P
E
L
L
A
V
G
V
V
D
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P01014
388
43754
V150
R
Q
L
I
N
S
W
V
E
K
E
T
N
G
Q
Frog
Xenopus laevis
Q52L45
377
42679
P146
E
Q
T
K
G
K
I
P
E
V
L
S
T
G
T
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.1
89.7
66.9
N.A.
52.5
50
N.A.
N.A.
45.1
48.4
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.2
95.1
81.2
N.A.
74.3
64.8
N.A.
N.A.
63.5
65.9
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
13.3
N.A.
N.A.
6.6
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
26.6
N.A.
N.A.
13.3
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
13
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
13
0
% D
% Glu:
88
0
0
0
0
13
0
0
25
0
75
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
13
0
0
13
0
0
0
0
0
13
0
0
25
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
25
0
63
13
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
13
75
63
13
0
0
0
13
0
0
0
0
0
% K
% Leu:
0
0
13
0
0
0
13
13
0
0
13
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
13
0
63
0
0
0
0
0
13
0
63
% N
% Pro:
0
0
0
0
13
0
0
13
0
0
0
0
0
0
0
% P
% Gln:
0
25
0
0
0
0
0
0
0
0
0
0
63
0
13
% Q
% Arg:
13
0
63
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
63
0
0
0
13
0
63
0
0
0
75
0
0
13
% S
% Thr:
0
0
13
0
0
0
0
0
0
0
0
13
13
63
13
% T
% Val:
0
0
0
0
0
0
0
13
0
88
0
13
13
0
0
% V
% Trp:
0
0
0
0
0
0
13
0
63
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _