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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PML
All Species:
13.03
Human Site:
S565
Identified Species:
57.33
UniProt:
P29590
Number Species:
5
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P29590
NP_002666.1
882
97551
S565
V
I
S
S
S
E
D
S
D
A
E
N
S
S
S
Chimpanzee
Pan troglodytes
NP_001035900
884
97717
S567
V
I
S
S
S
E
D
S
D
A
E
N
S
S
S
Rhesus Macaque
Macaca mulatta
NP_001035899
882
97390
S565
V
I
S
S
S
E
D
S
D
A
E
N
S
S
S
Dog
Lupus familis
XP_544766
591
64438
E318
K
A
I
K
M
E
S
E
E
E
R
E
T
R
L
Cat
Felis silvestris
Mouse
Mus musculus
Q60953
885
98224
S575
V
I
S
S
S
E
D
S
D
T
E
N
L
S
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507842
526
58839
Q253
M
Q
L
Y
A
S
D
Q
E
V
L
E
M
Y
P
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
95.2
38.8
N.A.
65.6
N.A.
N.A.
29.2
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.6
97.3
46.7
N.A.
77
N.A.
N.A.
41.8
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
6.6
N.A.
86.6
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
20
N.A.
86.6
N.A.
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
17
0
0
17
0
0
0
0
50
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
84
0
67
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
84
0
17
34
17
67
34
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
67
17
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
17
0
0
17
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
17
0
0
0
0
0
0
0
17
0
17
0
17
% L
% Met:
17
0
0
0
17
0
0
0
0
0
0
0
17
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
67
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
17
% P
% Gln:
0
17
0
0
0
0
0
17
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
17
0
0
17
0
% R
% Ser:
0
0
67
67
67
17
17
67
0
0
0
0
50
67
67
% S
% Thr:
0
0
0
0
0
0
0
0
0
17
0
0
17
0
0
% T
% Val:
67
0
0
0
0
0
0
0
0
17
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
17
0
0
0
0
0
0
0
0
0
17
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _