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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDHA2
All Species:
40.3
Human Site:
S310
Identified Species:
68.21
UniProt:
P29803
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P29803
NP_005381.1
388
42933
S310
E
E
I
Q
E
V
R
S
K
R
D
P
I
I
I
Chimpanzee
Pan troglodytes
A5A6L0
390
43219
S312
E
E
I
Q
E
V
R
S
K
S
D
P
I
M
L
Rhesus Macaque
Macaca mulatta
XP_001097880
420
46631
S342
D
E
I
Q
E
V
R
S
K
R
D
P
I
M
I
Dog
Lupus familis
XP_537975
390
43375
S312
E
E
I
Q
E
V
R
S
K
S
D
P
I
M
L
Cat
Felis silvestris
Mouse
Mus musculus
P35486
390
43213
S312
E
E
I
Q
E
V
R
S
K
S
D
P
I
M
L
Rat
Rattus norvegicus
P26284
390
43208
S312
E
E
I
Q
E
V
R
S
K
S
D
P
I
M
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514100
568
62886
S490
E
E
I
Q
E
V
R
S
K
S
D
P
I
T
L
Chicken
Gallus gallus
NP_001012562
399
44424
S319
E
E
I
Q
E
V
R
S
K
S
D
P
I
T
L
Frog
Xenopus laevis
NP_001087610
400
44764
S322
E
E
I
Q
E
V
R
S
K
S
D
P
I
T
L
Zebra Danio
Brachydanio rerio
NP_001002399
393
43605
S315
E
E
I
Q
E
V
R
S
K
S
D
P
I
T
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P52899
397
43773
K306
E
E
I
Q
E
V
R
K
T
R
D
P
I
T
G
Sea Urchin
Strong. purpuratus
XP_001175746
386
42313
Q310
E
E
V
Q
E
I
R
Q
S
Q
D
P
I
T
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P52901
389
43041
Q311
D
E
I
S
G
V
R
Q
E
R
D
P
I
E
R
Baker's Yeast
Sacchar. cerevisiae
P16387
420
46325
S332
D
E
I
Q
H
M
R
S
K
N
D
P
I
A
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
84.6
88.3
84.8
N.A.
85.3
84.8
N.A.
56.6
76.4
74.7
73.2
N.A.
N.A.
N.A.
56.4
56.9
Protein Similarity:
100
90.7
90.7
91.2
N.A.
91
90.7
N.A.
62.5
85.7
86.7
87.2
N.A.
N.A.
N.A.
70
71.9
P-Site Identity:
100
80
86.6
80
N.A.
80
80
N.A.
80
80
80
80
N.A.
N.A.
N.A.
73.3
53.3
P-Site Similarity:
100
93.3
100
93.3
N.A.
93.3
93.3
N.A.
86.6
86.6
86.6
80
N.A.
N.A.
N.A.
73.3
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
49.8
46.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
65.3
62.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
53.3
60
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
22
0
0
0
0
0
0
0
0
0
100
0
0
0
0
% D
% Glu:
79
100
0
0
86
0
0
0
8
0
0
0
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
15
% G
% His:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
93
0
0
8
0
0
0
0
0
0
100
8
15
% I
% Lys:
0
0
0
0
0
0
0
8
79
0
0
0
0
0
8
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
50
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
0
36
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
100
0
0
0
% P
% Gln:
0
0
0
93
0
0
0
15
0
8
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
100
0
0
29
0
0
0
0
8
% R
% Ser:
0
0
0
8
0
0
0
79
8
58
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
8
0
0
0
0
43
8
% T
% Val:
0
0
8
0
0
86
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _