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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDHA2
All Species:
40
Human Site:
T68
Identified Species:
67.69
UniProt:
P29803
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P29803
NP_005381.1
388
42933
T68
K
Y
Y
R
M
M
L
T
V
R
R
M
E
L
K
Chimpanzee
Pan troglodytes
A5A6L0
390
43219
T70
K
Y
Y
R
M
M
Q
T
V
R
R
M
E
L
K
Rhesus Macaque
Macaca mulatta
XP_001097880
420
46631
T100
K
Y
Y
R
M
M
L
T
V
R
R
M
E
L
K
Dog
Lupus familis
XP_537975
390
43375
T70
R
Y
Y
R
M
M
Q
T
V
R
R
M
E
L
K
Cat
Felis silvestris
Mouse
Mus musculus
P35486
390
43213
T70
K
Y
Y
R
M
M
Q
T
V
R
R
M
E
L
K
Rat
Rattus norvegicus
P26284
390
43208
T70
K
Y
Y
R
M
M
Q
T
V
R
R
M
E
L
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514100
568
62886
T248
K
Y
Y
R
T
M
Q
T
I
R
R
M
E
L
K
Chicken
Gallus gallus
NP_001012562
399
44424
T77
H
Y
Y
K
T
M
Q
T
I
R
R
M
E
L
K
Frog
Xenopus laevis
NP_001087610
400
44764
T80
Q
Y
Y
R
T
M
Q
T
I
R
R
M
E
L
K
Zebra Danio
Brachydanio rerio
NP_001002399
393
43605
T73
K
Y
Y
R
M
M
Q
T
M
R
R
M
E
L
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P52899
397
43773
E69
M
Q
V
I
R
R
M
E
S
A
A
G
N
L
Y
Sea Urchin
Strong. purpuratus
XP_001175746
386
42313
T68
D
Y
Y
H
K
M
Q
T
I
R
R
M
E
T
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P52901
389
43041
L68
D
F
F
R
T
M
A
L
M
R
R
M
E
I
A
Baker's Yeast
Sacchar. cerevisiae
P16387
420
46325
I90
Q
M
Y
K
D
M
V
I
I
R
R
M
E
M
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
84.6
88.3
84.8
N.A.
85.3
84.8
N.A.
56.6
76.4
74.7
73.2
N.A.
N.A.
N.A.
56.4
56.9
Protein Similarity:
100
90.7
90.7
91.2
N.A.
91
90.7
N.A.
62.5
85.7
86.7
87.2
N.A.
N.A.
N.A.
70
71.9
P-Site Identity:
100
93.3
100
86.6
N.A.
93.3
93.3
N.A.
80
66.6
73.3
86.6
N.A.
N.A.
N.A.
6.6
53.3
P-Site Similarity:
100
93.3
100
93.3
N.A.
93.3
93.3
N.A.
86.6
80
86.6
93.3
N.A.
N.A.
N.A.
13.3
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
49.8
46.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
65.3
62.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
40
40
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
8
0
0
8
8
0
0
0
22
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
15
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
8
0
0
0
0
93
0
0
% E
% Phe:
0
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% G
% His:
8
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
0
8
36
0
0
0
0
8
0
% I
% Lys:
50
0
0
15
8
0
0
0
0
0
0
0
0
0
72
% K
% Leu:
0
0
0
0
0
0
15
8
0
0
0
0
0
79
0
% L
% Met:
8
8
0
0
50
93
8
0
15
0
0
93
0
8
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
15
8
0
0
0
0
65
0
0
0
0
0
0
0
0
% Q
% Arg:
8
0
0
72
8
8
0
0
0
93
93
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
29
0
0
79
0
0
0
0
0
8
0
% T
% Val:
0
0
8
0
0
0
8
0
43
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
79
86
0
0
0
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _