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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CD40LG All Species: 14.55
Human Site: S12 Identified Species: 35.56
UniProt: P29965 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P29965 NP_000065.1 261 29274 S12 Y N Q T S P R S A A T G L P I
Chimpanzee Pan troglodytes Q8HZD9 232 25428
Rhesus Macaque Macaca mulatta P63304 261 29347 S12 Y N Q P S P R S A A T G L P V
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus P27548 260 29351 S12 Y S Q P S P R S V A T G L P A
Rat Rattus norvegicus Q9Z2V2 260 29241 S12 Y S Q P S P R S V A T G L P A
Wallaby Macropus eugenll O77764 233 25678
Platypus Ornith. anatinus XP_001514178 257 28816 S12 Y S Q P S P R S V N T G S P A
Chicken Gallus gallus Q9I8D8 272 30814 P12 Y S P A A P R P M G S T S P S
Frog Xenopus laevis NP_001163916 324 36218 Q40 G S E A G G K Q G L S R E G S
Zebra Danio Brachydanio rerio NP_571918 317 35447 N26 T Y M M V P A N S R G R D S P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 24.1 98 N.A. N.A. 77.3 77 21.8 49.8 38.9 20 23 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 39.4 98.8 N.A. N.A. 86.2 85.4 40.6 68.5 61 41.9 43.2 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 0 86.6 N.A. N.A. 73.3 73.3 0 60 26.6 0 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 0 93.3 N.A. N.A. 80 80 0 66.6 46.6 26.6 20 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 20 10 0 10 0 20 40 0 0 0 0 30 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % D
% Glu: 0 0 10 0 0 0 0 0 0 0 0 0 10 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 0 0 0 10 10 0 0 10 10 10 50 0 10 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % I
% Lys: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 10 0 0 40 0 0 % L
% Met: 0 0 10 10 0 0 0 0 10 0 0 0 0 0 0 % M
% Asn: 0 20 0 0 0 0 0 10 0 10 0 0 0 0 0 % N
% Pro: 0 0 10 40 0 70 0 10 0 0 0 0 0 60 10 % P
% Gln: 0 0 50 0 0 0 0 10 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 60 0 0 10 0 20 0 0 0 % R
% Ser: 0 50 0 0 50 0 0 50 10 0 20 0 20 10 20 % S
% Thr: 10 0 0 10 0 0 0 0 0 0 50 10 0 0 0 % T
% Val: 0 0 0 0 10 0 0 0 30 0 0 0 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 60 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _