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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CD40LG
All Species:
22.42
Human Site:
Y45
Identified Species:
54.81
UniProt:
P29965
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P29965
NP_000065.1
261
29274
Y45
G
S
A
L
F
A
V
Y
L
H
R
R
L
D
K
Chimpanzee
Pan troglodytes
Q8HZD9
232
25428
R29
G
G
P
Q
G
S
R
R
C
L
F
L
S
L
F
Rhesus Macaque
Macaca mulatta
P63304
261
29347
Y45
G
S
A
L
F
A
V
Y
L
H
R
R
L
D
K
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P27548
260
29351
Y45
G
S
V
L
F
A
V
Y
L
H
R
R
L
D
K
Rat
Rattus norvegicus
Q9Z2V2
260
29241
Y45
G
S
V
P
F
A
V
Y
L
H
R
R
L
D
K
Wallaby
Macropus eugenll
O77764
233
25678
C30
G
P
Q
G
P
G
R
C
L
C
L
I
L
T
F
Platypus
Ornith. anatinus
XP_001514178
257
28816
Y45
A
T
A
L
F
G
I
Y
L
H
R
R
L
D
K
Chicken
Gallus gallus
Q9I8D8
272
30814
Y45
G
T
V
L
F
C
L
Y
L
H
M
K
M
D
K
Frog
Xenopus laevis
NP_001163916
324
36218
F73
T
T
G
L
F
V
Y
F
S
V
S
I
S
K
L
Zebra Danio
Brachydanio rerio
NP_571918
317
35447
Y59
S
T
T
G
L
F
V
Y
L
N
M
S
L
S
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
24.1
98
N.A.
N.A.
77.3
77
21.8
49.8
38.9
20
23
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
39.4
98.8
N.A.
N.A.
86.2
85.4
40.6
68.5
61
41.9
43.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
100
N.A.
N.A.
93.3
86.6
20
73.3
53.3
13.3
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
100
N.A.
N.A.
93.3
86.6
20
86.6
80
26.6
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
30
0
0
40
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
10
0
10
10
10
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
60
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
70
10
0
10
0
0
10
0
0
0
20
% F
% Gly:
70
10
10
20
10
20
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
60
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
10
0
0
0
0
20
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
10
0
10
60
% K
% Leu:
0
0
0
60
10
0
10
0
80
10
10
10
70
10
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
20
0
10
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% N
% Pro:
0
10
10
10
10
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
10
10
0
0
0
0
0
0
0
0
0
0
10
% Q
% Arg:
0
0
0
0
0
0
20
10
0
0
50
50
0
0
0
% R
% Ser:
10
40
0
0
0
10
0
0
10
0
10
10
20
10
0
% S
% Thr:
10
40
10
0
0
0
0
0
0
0
0
0
0
10
0
% T
% Val:
0
0
30
0
0
10
50
0
0
10
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
10
70
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _