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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: C21orf33 All Species: 15.15
Human Site: S22 Identified Species: 33.33
UniProt: P30042 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P30042 NP_004640.2 268 28170 S22 A S A F T S L S P G G R T P S
Chimpanzee Pan troglodytes XP_001149433 268 28138 S22 A S A F T S L S P G G R T P S
Rhesus Macaque Macaca mulatta XP_001103777 268 27971 S22 A S A F A S L S P G G R T P S
Dog Lupus familis XP_854067 236 25610 Y32 T C K R K C T Y R V L V H L S
Cat Felis silvestris
Mouse Mus musculus Q9D172 266 28072 S20 A S A L L P L S R Y H R A P S
Rat Rattus norvegicus P56571 266 28154 S20 A S A L L P L S G R H R T T S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512318 265 28394 S25 C F P N A V P S V S S G I Q I
Chicken Gallus gallus NP_001025969 259 27353 G20 L R R A A P C G F A S F H C S
Frog Xenopus laevis NP_001167509 256 26653 A32 V S Q G K P A A K V A V V L S
Zebra Danio Brachydanio rerio Q90257 270 30667 A21 A M L V R Q P A C L M H H G G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_787091 227 23781 S25 G S E V H E A S A V W V H L S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 94.4 71.2 N.A. 89.5 88.4 N.A. 75 75.7 68.2 49.6 N.A. N.A. N.A. N.A. 59.7
Protein Similarity: 100 99.6 96.6 77.6 N.A. 91.7 91.7 N.A. 81.7 82.8 77.9 67.4 N.A. N.A. N.A. N.A. 71.2
P-Site Identity: 100 100 93.3 6.6 N.A. 53.3 53.3 N.A. 6.6 6.6 13.3 6.6 N.A. N.A. N.A. N.A. 20
P-Site Similarity: 100 100 93.3 6.6 N.A. 53.3 53.3 N.A. 6.6 6.6 20 13.3 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 55 0 46 10 28 0 19 19 10 10 10 0 10 0 0 % A
% Cys: 10 10 0 0 0 10 10 0 10 0 0 0 0 10 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 10 0 0 10 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 10 0 28 0 0 0 0 10 0 0 10 0 0 0 % F
% Gly: 10 0 0 10 0 0 0 10 10 28 28 10 0 10 10 % G
% His: 0 0 0 0 10 0 0 0 0 0 19 10 37 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 10 % I
% Lys: 0 0 10 0 19 0 0 0 10 0 0 0 0 0 0 % K
% Leu: 10 0 10 19 19 0 46 0 0 10 10 0 0 28 0 % L
% Met: 0 10 0 0 0 0 0 0 0 0 10 0 0 0 0 % M
% Asn: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 10 0 0 37 19 0 28 0 0 0 0 37 0 % P
% Gln: 0 0 10 0 0 10 0 0 0 0 0 0 0 10 0 % Q
% Arg: 0 10 10 10 10 0 0 0 19 10 0 46 0 0 0 % R
% Ser: 0 64 0 0 0 28 0 64 0 10 19 0 0 0 82 % S
% Thr: 10 0 0 0 19 0 10 0 0 0 0 0 37 10 0 % T
% Val: 10 0 0 19 0 10 0 0 10 28 0 28 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 10 0 10 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _