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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GCHFR All Species: 23.33
Human Site: Y45 Identified Species: 64.17
UniProt: P30047 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P30047 NP_005249.1 84 9698 Y45 R A L G N N F Y E Y Y V D D P
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001097382 271 28972 Y232 S V L G N N F Y E Y Y V N D P
Dog Lupus familis XP_544622 84 9631 Y45 S V L G N N F Y E Y F V N D P
Cat Felis silvestris
Mouse Mus musculus P99025 84 9566 Y45 S V L G N N F Y E Y Y V N D P
Rat Rattus norvegicus P70552 84 9654 Y45 R V L G N N F Y E Y Y V N D P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511888 75 8437 D42 F W E Y Y V N D P P R V V L D
Chicken Gallus gallus XP_420935 84 9614 W45 N M L G N H F W E Y Y V N D A
Frog Xenopus laevis Q6GM84 84 9545 S45 T V L G N N F S E Y Y V N E P
Zebra Danio Brachydanio rerio Q6PBT6 89 9999 S45 T V L G N N F S E Y H V D E P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 29.8 88 N.A. 92.8 94 N.A. 71.4 82.1 75 70.7 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 N.A. 30.2 95.2 N.A. 95.2 95.2 N.A. 79.7 90.4 84.5 83.1 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 N.A. 80 73.3 N.A. 80 86.6 N.A. 6.6 60 66.6 66.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 N.A. 86.6 86.6 N.A. 86.6 93.3 N.A. 6.6 80 80 80 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 12 0 0 0 0 0 0 0 0 0 0 0 0 12 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 12 0 0 0 0 23 67 12 % D
% Glu: 0 0 12 0 0 0 0 0 89 0 0 0 0 23 0 % E
% Phe: 12 0 0 0 0 0 89 0 0 0 12 0 0 0 0 % F
% Gly: 0 0 0 89 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 12 0 0 0 0 12 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 89 0 0 0 0 0 0 0 0 0 0 12 0 % L
% Met: 0 12 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 12 0 0 0 89 78 12 0 0 0 0 0 67 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 12 12 0 0 0 0 78 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 23 0 0 0 0 0 0 0 0 0 12 0 0 0 0 % R
% Ser: 34 0 0 0 0 0 0 23 0 0 0 0 0 0 0 % S
% Thr: 23 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 67 0 0 0 12 0 0 0 0 0 100 12 0 0 % V
% Trp: 0 12 0 0 0 0 0 12 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 12 12 0 0 56 0 89 67 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _