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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ECHS1
All Species:
32.12
Human Site:
T269
Identified Species:
70.67
UniProt:
P30084
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P30084
NP_004083.3
290
31387
T269
L
F
Y
S
T
F
A
T
D
D
R
K
E
G
M
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537945
575
62826
T554
L
F
Y
A
T
F
A
T
E
D
R
K
E
G
M
Cat
Felis silvestris
Mouse
Mus musculus
Q8BH95
290
31456
T269
L
F
Y
S
T
F
A
T
D
D
R
R
E
G
M
Rat
Rattus norvegicus
P14604
290
31498
T269
L
F
Y
S
T
F
A
T
D
D
R
R
E
G
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513497
401
42660
T362
L
F
Y
S
T
F
A
T
I
X
X
X
X
R
T
Chicken
Gallus gallus
Frog
Xenopus laevis
A9JS71
294
32171
M273
V
M
V
E
N
L
A
M
K
D
G
Q
E
G
L
Zebra Danio
Brachydanio rerio
A0PJR5
289
31421
L263
A
M
L
D
N
L
R
L
R
D
G
Q
E
G
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610910
295
31564
T274
T
F
H
A
T
F
S
T
A
D
R
K
E
G
M
Honey Bee
Apis mellifera
XP_001123353
268
29301
T247
I
F
H
G
T
F
A
T
D
D
R
K
E
G
M
Nematode Worm
Caenorhab. elegans
P34559
288
31153
T267
L
F
H
A
T
F
A
T
K
D
R
K
E
G
M
Sea Urchin
Strong. purpuratus
XP_781169
295
31417
T274
L
F
H
A
C
F
G
T
E
D
A
R
E
G
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
44.5
N.A.
87.5
86.9
N.A.
54.8
N.A.
31.2
29.6
N.A.
54.9
57.2
56.9
61.6
Protein Similarity:
100
N.A.
N.A.
48
N.A.
92.7
93.4
N.A.
61.8
N.A.
48.6
48.6
N.A.
71.5
72
70.6
74.5
P-Site Identity:
100
N.A.
N.A.
86.6
N.A.
93.3
93.3
N.A.
53.3
N.A.
26.6
20
N.A.
66.6
80
80
53.3
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
53.3
N.A.
46.6
33.3
N.A.
86.6
93.3
93.3
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
37
0
0
73
0
10
0
10
0
0
0
0
% A
% Cys:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
0
0
37
91
0
0
0
0
0
% D
% Glu:
0
0
0
10
0
0
0
0
19
0
0
0
91
0
0
% E
% Phe:
0
82
0
0
0
82
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
10
0
0
10
0
0
0
19
0
0
91
0
% G
% His:
0
0
37
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
0
0
0
10
0
0
0
0
0
10
% I
% Lys:
0
0
0
0
0
0
0
0
19
0
0
46
0
0
0
% K
% Leu:
64
0
10
0
0
19
0
10
0
0
0
0
0
0
10
% L
% Met:
0
19
0
0
0
0
0
10
0
0
0
0
0
0
73
% M
% Asn:
0
0
0
0
19
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
19
0
0
0
% Q
% Arg:
0
0
0
0
0
0
10
0
10
0
64
28
0
10
0
% R
% Ser:
0
0
0
37
0
0
10
0
0
0
0
0
0
0
0
% S
% Thr:
10
0
0
0
73
0
0
82
0
0
0
0
0
0
10
% T
% Val:
10
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
46
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _