KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ECHS1
All Species:
25.45
Human Site:
T277
Identified Species:
56
UniProt:
P30084
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P30084
NP_004083.3
290
31387
T277
D
D
R
K
E
G
M
T
A
F
V
E
K
R
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537945
575
62826
T562
E
D
R
K
E
G
M
T
A
F
V
E
K
R
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8BH95
290
31456
T277
D
D
R
R
E
G
M
T
A
F
V
E
K
R
K
Rat
Rattus norvegicus
P14604
290
31498
S277
D
D
R
R
E
G
M
S
A
F
V
E
K
R
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513497
401
42660
H370
I
X
X
X
X
R
T
H
G
P
R
G
G
G
R
Chicken
Gallus gallus
Frog
Xenopus laevis
A9JS71
294
32171
K281
K
D
G
Q
E
G
L
K
S
F
I
Q
K
R
K
Zebra Danio
Brachydanio rerio
A0PJR5
289
31421
R271
R
D
G
Q
E
G
I
R
A
F
L
E
K
R
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610910
295
31564
T282
A
D
R
K
E
G
M
T
A
F
A
E
K
R
P
Honey Bee
Apis mellifera
XP_001123353
268
29301
T255
D
D
R
K
E
G
M
T
A
F
I
E
K
R
S
Nematode Worm
Caenorhab. elegans
P34559
288
31153
T275
K
D
R
K
E
G
M
T
A
F
A
E
K
R
K
Sea Urchin
Strong. purpuratus
XP_781169
295
31417
G282
E
D
A
R
E
G
M
G
A
F
V
G
K
R
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
44.5
N.A.
87.5
86.9
N.A.
54.8
N.A.
31.2
29.6
N.A.
54.9
57.2
56.9
61.6
Protein Similarity:
100
N.A.
N.A.
48
N.A.
92.7
93.4
N.A.
61.8
N.A.
48.6
48.6
N.A.
71.5
72
70.6
74.5
P-Site Identity:
100
N.A.
N.A.
93.3
N.A.
93.3
86.6
N.A.
0
N.A.
46.6
60
N.A.
80
86.6
86.6
60
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
6.6
N.A.
80
80
N.A.
80
93.3
86.6
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
0
0
0
0
0
82
0
19
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
37
91
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
19
0
0
0
91
0
0
0
0
0
0
73
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
91
0
0
0
0
0
% F
% Gly:
0
0
19
0
0
91
0
10
10
0
0
19
10
10
0
% G
% His:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
0
10
0
0
0
19
0
0
0
0
% I
% Lys:
19
0
0
46
0
0
0
10
0
0
0
0
91
0
64
% K
% Leu:
0
0
0
0
0
0
10
0
0
0
10
0
0
0
0
% L
% Met:
0
0
0
0
0
0
73
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
10
% P
% Gln:
0
0
0
19
0
0
0
0
0
0
0
10
0
0
0
% Q
% Arg:
10
0
64
28
0
10
0
10
0
0
10
0
0
91
10
% R
% Ser:
0
0
0
0
0
0
0
10
10
0
0
0
0
0
10
% S
% Thr:
0
0
0
0
0
0
10
55
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
46
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _