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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PDIA3 All Species: 29.7
Human Site: S150 Identified Species: 40.83
UniProt: P30101 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0.19
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P30101 NP_005304.3 505 56782 S150 E E F K K F I S D K D A S I V
Chimpanzee Pan troglodytes XP_001159528 485 54945 S130 E E F K K F I S D K D A S I V
Rhesus Macaque Macaca mulatta XP_001108948 480 54081 S125 E E F K K F I S D K D A S V V
Dog Lupus familis XP_535453 687 75990 S332 E E F E K F I S D K D A S V V
Cat Felis silvestris
Mouse Mus musculus P27773 505 56660 S150 E E F K K F I S D K D A S V V
Rat Rattus norvegicus P11598 505 56605 S150 D E F K K F I S D K D A S V V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517928 483 54617 S127 D E F E K F I S D K D A S V V
Chicken Gallus gallus Q8JG64 505 56163 G148 A D F E K F I G D K D A S V V
Frog Xenopus laevis NP_001080051 502 56103 A146 E E F E K F V A D K D A A V V
Zebra Danio Brachydanio rerio NP_998070 488 54656 D142 A D L D G F V D N Y E A S V V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P54399 496 55763 D152 D A E Q F L K D N E I A I I G
Honey Bee Apis mellifera XP_623282 490 55838 D147 N C L K S F L D S D E V S V V
Nematode Worm Caenorhab. elegans P34329 618 69779 K272 D V E R F M S K D D V T I I G
Sea Urchin Strong. purpuratus XP_782981 472 51996 S141 A Q F D D F T S G A T A A I V
Poplar Tree Populus trichocarpa
Maize Zea mays P52588 513 57078 D162 E D A T A L I D D K K I Y I V
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SRG3 508 56346 G157 D S A T E V V G E K N V V A V
Baker's Yeast Sacchar. cerevisiae P17967 522 58209 N155 D L P A Y L A N E T F V T P V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 91 94.4 70.8 N.A. 93 92.2 N.A. 84.7 80.9 74.6 60 N.A. 32.6 49.5 36.7 50.5
Protein Similarity: 100 92.6 94.8 72.1 N.A. 97 96.2 N.A. 90.3 90.8 88.3 77.2 N.A. 53.4 63.7 50.4 65.9
P-Site Identity: 100 100 93.3 86.6 N.A. 93.3 86.6 N.A. 80 66.6 66.6 26.6 N.A. 13.3 26.6 13.3 40
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 86.6 100 60 N.A. 40 46.6 26.6 53.3
Percent
Protein Identity: N.A. 34.3 N.A. 35.6 26.8 N.A.
Protein Similarity: N.A. 51 N.A. 54.9 48.4 N.A.
P-Site Identity: N.A. 40 N.A. 13.3 6.6 N.A.
P-Site Similarity: N.A. 46.6 N.A. 46.6 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 18 6 12 6 6 0 6 6 0 6 0 71 12 6 0 % A
% Cys: 0 6 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 36 18 0 12 6 0 0 24 65 12 53 0 0 0 0 % D
% Glu: 42 48 12 24 6 0 0 0 12 6 12 0 0 0 0 % E
% Phe: 0 0 59 0 12 71 0 0 0 0 6 0 0 0 0 % F
% Gly: 0 0 0 0 6 0 0 12 6 0 0 0 0 0 12 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 53 0 0 0 6 6 12 36 0 % I
% Lys: 0 0 0 36 53 0 6 6 0 65 6 0 0 0 0 % K
% Leu: 0 6 12 0 0 18 6 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 6 0 0 0 0 0 0 0 0 0 % M
% Asn: 6 0 0 0 0 0 0 6 12 0 6 0 0 0 0 % N
% Pro: 0 0 6 0 0 0 0 0 0 0 0 0 0 6 0 % P
% Gln: 0 6 0 6 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 6 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 6 0 0 6 0 6 48 6 0 0 0 59 0 0 % S
% Thr: 0 0 0 12 0 0 6 0 0 6 6 6 6 0 0 % T
% Val: 0 6 0 0 0 6 18 0 0 0 6 18 6 53 89 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 6 0 0 0 0 6 0 0 6 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _