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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PDIA3 All Species: 45.15
Human Site: S343 Identified Species: 62.08
UniProt: P30101 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0.06
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P30101 NP_005304.3 505 56782 S343 F V M Q E E F S R D G K A L E
Chimpanzee Pan troglodytes XP_001159528 485 54945 S323 F V M Q E E F S R D G K A L E
Rhesus Macaque Macaca mulatta XP_001108948 480 54081 S318 F V M Q E E F S R D G K A L E
Dog Lupus familis XP_535453 687 75990 S525 F V M Q E E F S R D G K A L E
Cat Felis silvestris
Mouse Mus musculus P27773 505 56660 S343 F V M Q E E F S R D G K A L E
Rat Rattus norvegicus P11598 505 56605 S343 F V M Q E E F S R D G K A L E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517928 483 54617 S320 F V M Q E E F S R D G K A L E
Chicken Gallus gallus Q8JG64 505 56163 S341 F V M Q E E F S R D G K A L E
Frog Xenopus laevis NP_001080051 502 56103 S340 F V M Q E E F S R D G K A L E
Zebra Danio Brachydanio rerio NP_998070 488 54656 T334 Y S M Q E E F T R D G K S L E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P54399 496 55763 D333 K Y K P E S D D L S A E T I E
Honey Bee Apis mellifera XP_623282 490 55838 S331 F V M K D E F S V S T F E A F
Nematode Worm Caenorhab. elegans P34329 618 69779 G466 M N P D E F D G E L D E N L E
Sea Urchin Strong. purpuratus XP_782981 472 51996 T322 F V M P E K F T V K T L K A F
Poplar Tree Populus trichocarpa
Maize Zea mays P52588 513 57078 H345 S K K F L K V H V E A D Q I V
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SRG3 508 56346 N339 N K K Y L K V N V E V D Q I E
Baker's Yeast Sacchar. cerevisiae P17967 522 58209 V343 D E L S D K I V L E S K A I E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 91 94.4 70.8 N.A. 93 92.2 N.A. 84.7 80.9 74.6 60 N.A. 32.6 49.5 36.7 50.5
Protein Similarity: 100 92.6 94.8 72.1 N.A. 97 96.2 N.A. 90.3 90.8 88.3 77.2 N.A. 53.4 63.7 50.4 65.9
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 100 100 100 73.3 N.A. 13.3 40 20 33.3
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 100 100 93.3 N.A. 26.6 53.3 26.6 46.6
Percent
Protein Identity: N.A. 34.3 N.A. 35.6 26.8 N.A.
Protein Similarity: N.A. 51 N.A. 54.9 48.4 N.A.
P-Site Identity: N.A. 0 N.A. 6.6 20 N.A.
P-Site Similarity: N.A. 20 N.A. 33.3 53.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 12 0 59 12 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 6 0 0 6 12 0 12 6 0 59 6 12 0 0 0 % D
% Glu: 0 6 0 0 77 65 0 0 6 18 0 12 6 0 83 % E
% Phe: 65 0 0 6 0 6 71 0 0 0 0 6 0 0 12 % F
% Gly: 0 0 0 0 0 0 0 6 0 0 59 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 6 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 6 0 0 0 0 0 0 24 0 % I
% Lys: 6 12 18 6 0 24 0 0 0 6 0 65 6 0 0 % K
% Leu: 0 0 6 0 12 0 0 0 12 6 0 6 0 65 0 % L
% Met: 6 0 71 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 6 6 0 0 0 0 0 6 0 0 0 0 6 0 0 % N
% Pro: 0 0 6 12 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 59 0 0 0 0 0 0 0 0 12 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 59 0 0 0 0 0 0 % R
% Ser: 6 6 0 6 0 6 0 59 0 12 6 0 6 0 0 % S
% Thr: 0 0 0 0 0 0 0 12 0 0 12 0 6 0 0 % T
% Val: 0 65 0 0 0 0 12 6 24 0 6 0 0 0 6 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 6 6 0 6 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _