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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDIA3
All Species:
33.33
Human Site:
S373
Identified Species:
45.83
UniProt:
P30101
Number Species:
16
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P30101
NP_005304.3
505
56782
S373
K
S
E
P
I
P
E
S
N
D
G
P
V
K
V
Chimpanzee
Pan troglodytes
XP_001159528
485
54945
S353
K
S
E
P
I
P
E
S
N
D
G
P
V
K
V
Rhesus Macaque
Macaca mulatta
XP_001108948
480
54081
S348
K
S
E
P
I
P
E
S
N
D
G
P
V
K
V
Dog
Lupus familis
XP_535453
687
75990
S555
K
S
E
P
I
P
E
S
N
D
G
P
V
K
V
Cat
Felis silvestris
Mouse
Mus musculus
P27773
505
56660
S373
K
S
E
P
I
P
E
S
N
E
G
P
V
K
V
Rat
Rattus norvegicus
P11598
505
56605
T373
K
S
E
P
I
P
E
T
N
E
G
P
V
K
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517928
483
54617
N350
K
S
E
P
V
P
E
N
N
D
G
P
V
K
V
Chicken
Gallus gallus
Q8JG64
505
56163
N371
K
S
E
P
V
P
E
N
N
D
G
P
V
K
V
Frog
Xenopus laevis
NP_001080051
502
56103
S370
K
S
E
S
I
P
E
S
N
D
G
P
V
K
V
Zebra Danio
Brachydanio rerio
NP_998070
488
54656
S364
K
S
E
P
I
P
E
S
N
D
G
P
V
K
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54399
496
55763
D363
L
S
Q
E
L
P
E
D
W
D
K
N
P
V
K
Honey Bee
Apis mellifera
XP_623282
490
55838
S361
E
P
I
P
E
D
N
S
G
N
V
K
I
A
V
Nematode Worm
Caenorhab. elegans
P34329
618
69779
D496
K
S
A
P
A
P
K
D
D
K
G
P
V
K
T
Sea Urchin
Strong. purpuratus
XP_782981
472
51996
D352
E
D
I
P
A
S
N
D
G
P
V
K
V
V
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P52588
513
57078
V375
N
S
E
P
I
P
E
V
N
N
E
P
V
K
V
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SRG3
508
56346
E369
K
S
Q
P
I
P
A
E
N
N
E
P
V
K
V
Baker's Yeast
Sacchar. cerevisiae
P17967
522
58209
N373
K
S
Q
E
I
F
E
N
Q
D
S
S
V
F
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91
94.4
70.8
N.A.
93
92.2
N.A.
84.7
80.9
74.6
60
N.A.
32.6
49.5
36.7
50.5
Protein Similarity:
100
92.6
94.8
72.1
N.A.
97
96.2
N.A.
90.3
90.8
88.3
77.2
N.A.
53.4
63.7
50.4
65.9
P-Site Identity:
100
100
100
100
N.A.
93.3
86.6
N.A.
86.6
86.6
93.3
100
N.A.
26.6
20
53.3
20
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
93.3
100
N.A.
40
40
66.6
26.6
Percent
Protein Identity:
N.A.
34.3
N.A.
35.6
26.8
N.A.
Protein Similarity:
N.A.
51
N.A.
54.9
48.4
N.A.
P-Site Identity:
N.A.
73.3
N.A.
66.6
40
N.A.
P-Site Similarity:
N.A.
80
N.A.
80
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
6
0
12
0
6
0
0
0
0
0
0
6
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
6
0
0
0
6
0
18
6
59
0
0
0
0
0
% D
% Glu:
12
0
65
12
6
0
77
6
0
12
12
0
0
0
0
% E
% Phe:
0
0
0
0
0
6
0
0
0
0
0
0
0
6
0
% F
% Gly:
0
0
0
0
0
0
0
0
12
0
65
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
12
0
65
0
0
0
0
0
0
0
6
0
0
% I
% Lys:
77
0
0
0
0
0
6
0
0
6
6
12
0
77
6
% K
% Leu:
6
0
0
0
6
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
6
0
0
0
0
0
12
18
71
18
0
6
0
0
0
% N
% Pro:
0
6
0
83
0
83
0
0
0
6
0
77
6
0
0
% P
% Gln:
0
0
18
0
0
0
0
0
6
0
0
0
0
0
6
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
89
0
6
0
6
0
48
0
0
6
6
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
6
0
0
0
0
0
0
6
% T
% Val:
0
0
0
0
12
0
0
6
0
0
12
0
89
12
83
% V
% Trp:
0
0
0
0
0
0
0
0
6
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _