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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PDIA3 All Species: 15.76
Human Site: S40 Identified Species: 21.67
UniProt: P30101 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P30101 NP_005304.3 505 56782 S40 D N F E S R I S D T G S A G L
Chimpanzee Pan troglodytes XP_001159528 485 54945 T24 S L A A Y T H T W L L P R F L
Rhesus Macaque Macaca mulatta XP_001108948 480 54081 A23 L A A A R L A A A S D F F A P
Dog Lupus familis XP_535453 687 75990 S222 D N F E S R I S D T G S A G L
Cat Felis silvestris
Mouse Mus musculus P27773 505 56660 S40 E N F E S R V S D T G S A G L
Rat Rattus norvegicus P11598 505 56605 S40 E N F E S R V S D T G S A G L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517928 483 54617 M25 D T G S A G L M L V E F F A P
Chicken Gallus gallus Q8JG64 505 56163 A40 A D F E S G L A E R P G L V L
Frog Xenopus laevis NP_001080051 502 56103 A39 D N F E S V V A Q H S I L L V
Zebra Danio Brachydanio rerio NP_998070 488 54656 G35 S D F D R S A G M H D T L L V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P54399 496 55763 A42 D N F K Q L I A D N E F V L V
Honey Bee Apis mellifera XP_623282 490 55838 E36 E T F S H E L E R L E N T L V
Nematode Worm Caenorhab. elegans P34329 618 69779 N31 D A S D D E L N Y E M D E G V
Sea Urchin Strong. purpuratus XP_782981 472 51996 G32 D D F K D N I G D H S L I L V
Poplar Tree Populus trichocarpa
Maize Zea mays P52588 513 57078 E46 L D V D S F D E A V A K H P F
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SRG3 508 56346 T42 D H S N F T E T I S K H D F I
Baker's Yeast Sacchar. cerevisiae P17967 522 58209 A28 F A Q Q E A V A P E D S A V V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 91 94.4 70.8 N.A. 93 92.2 N.A. 84.7 80.9 74.6 60 N.A. 32.6 49.5 36.7 50.5
Protein Similarity: 100 92.6 94.8 72.1 N.A. 97 96.2 N.A. 90.3 90.8 88.3 77.2 N.A. 53.4 63.7 50.4 65.9
P-Site Identity: 100 6.6 0 100 N.A. 86.6 86.6 N.A. 6.6 26.6 33.3 6.6 N.A. 33.3 6.6 13.3 26.6
P-Site Similarity: 100 13.3 13.3 100 N.A. 100 100 N.A. 20 53.3 53.3 33.3 N.A. 53.3 33.3 40 46.6
Percent
Protein Identity: N.A. 34.3 N.A. 35.6 26.8 N.A.
Protein Similarity: N.A. 51 N.A. 54.9 48.4 N.A.
P-Site Identity: N.A. 6.6 N.A. 6.6 13.3 N.A.
P-Site Similarity: N.A. 20 N.A. 33.3 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 6 18 12 12 6 6 12 30 12 0 6 0 30 12 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 48 24 0 18 12 0 6 0 36 0 18 6 6 0 0 % D
% Glu: 18 0 0 36 6 12 6 12 6 12 18 0 6 0 0 % E
% Phe: 6 0 59 0 6 6 0 0 0 0 0 18 12 12 6 % F
% Gly: 0 0 6 0 0 12 0 12 0 0 24 6 0 30 0 % G
% His: 0 6 0 0 6 0 6 0 0 18 0 6 6 0 0 % H
% Ile: 0 0 0 0 0 0 24 0 6 0 0 6 6 0 6 % I
% Lys: 0 0 0 12 0 0 0 0 0 0 6 6 0 0 0 % K
% Leu: 12 6 0 0 0 12 24 0 6 12 6 6 18 30 36 % L
% Met: 0 0 0 0 0 0 0 6 6 0 6 0 0 0 0 % M
% Asn: 0 36 0 6 0 6 0 6 0 6 0 6 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 6 0 6 6 0 6 12 % P
% Gln: 0 0 6 6 6 0 0 0 6 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 12 24 0 0 6 6 0 0 6 0 0 % R
% Ser: 12 0 12 12 42 6 0 24 0 12 12 30 0 0 0 % S
% Thr: 0 12 0 0 0 12 0 12 0 24 0 6 6 0 0 % T
% Val: 0 0 6 0 0 6 24 0 0 12 0 0 6 12 42 % V
% Trp: 0 0 0 0 0 0 0 0 6 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 6 0 0 0 6 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _