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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PDIA3 All Species: 27.27
Human Site: S474 Identified Species: 37.5
UniProt: P30101 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P30101 NP_005304.3 505 56782 S474 Y E G G R E L S D F I S Y L Q
Chimpanzee Pan troglodytes XP_001159528 485 54945 S454 Y E G G R E L S D F I S Y L Q
Rhesus Macaque Macaca mulatta XP_001108948 480 54081 S449 Y E G G R E L S D F I S Y L Q
Dog Lupus familis XP_535453 687 75990 S656 Y E G G R E L S D F I S Y L Q
Cat Felis silvestris
Mouse Mus musculus P27773 505 56660 N474 Y E G G R E L N D F I S Y L Q
Rat Rattus norvegicus P11598 505 56605 N474 Y E G G R E L N D F I S Y L Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517928 483 54617 S451 Y E G G R E V S D F L S Y L Q
Chicken Gallus gallus Q8JG64 505 56163 S472 Y E G G R E V S D F I S Y L K
Frog Xenopus laevis NP_001080051 502 56103 S471 Y E G G R E V S E F L S Y L K
Zebra Danio Brachydanio rerio NP_998070 488 54656 N465 Y E G G R E V N D F I T Y L K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P54399 496 55763 F465 L D R T L D D F V K F L D A N
Honey Bee Apis mellifera XP_623282 490 55838 D459 Y E G G R E L D D F I K Y I A
Nematode Worm Caenorhab. elegans P34329 618 69779 E598 Y S G N R D L E D L K K F M T
Sea Urchin Strong. purpuratus XP_782981 472 51996 P449 Y E G G R E V P D F I K F I K
Poplar Tree Populus trichocarpa
Maize Zea mays P52588 513 57078 I476 S G R T A D D I V D F I K K S
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SRG3 508 56346 D470 E G D R T K E D F I N F V E K
Baker's Yeast Sacchar. cerevisiae P17967 522 58209 D474 Y Q G S R S L D S L F D F I K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 91 94.4 70.8 N.A. 93 92.2 N.A. 84.7 80.9 74.6 60 N.A. 32.6 49.5 36.7 50.5
Protein Similarity: 100 92.6 94.8 72.1 N.A. 97 96.2 N.A. 90.3 90.8 88.3 77.2 N.A. 53.4 63.7 50.4 65.9
P-Site Identity: 100 100 100 100 N.A. 93.3 93.3 N.A. 86.6 86.6 73.3 73.3 N.A. 0 73.3 33.3 60
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 100 100 100 N.A. 13.3 80 53.3 86.6
Percent
Protein Identity: N.A. 34.3 N.A. 35.6 26.8 N.A.
Protein Similarity: N.A. 51 N.A. 54.9 48.4 N.A.
P-Site Identity: N.A. 0 N.A. 0 26.6 N.A.
P-Site Similarity: N.A. 6.6 N.A. 13.3 53.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 6 0 0 0 0 0 0 0 0 6 6 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 6 6 0 0 18 12 18 71 6 0 6 6 0 0 % D
% Glu: 6 71 0 0 0 71 6 6 6 0 0 0 0 6 0 % E
% Phe: 0 0 0 0 0 0 0 6 6 71 18 6 18 0 0 % F
% Gly: 0 12 83 71 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 6 0 6 59 6 0 18 0 % I
% Lys: 0 0 0 0 0 6 0 0 0 6 6 18 6 6 36 % K
% Leu: 6 0 0 0 6 0 53 0 0 12 12 6 0 59 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 6 0 % M
% Asn: 0 0 0 6 0 0 0 18 0 0 6 0 0 0 6 % N
% Pro: 0 0 0 0 0 0 0 6 0 0 0 0 0 0 0 % P
% Gln: 0 6 0 0 0 0 0 0 0 0 0 0 0 0 42 % Q
% Arg: 0 0 12 6 83 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 6 6 0 6 0 6 0 42 6 0 0 53 0 0 6 % S
% Thr: 0 0 0 12 6 0 0 0 0 0 0 6 0 0 6 % T
% Val: 0 0 0 0 0 0 30 0 12 0 0 0 6 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 83 0 0 0 0 0 0 0 0 0 0 0 65 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _