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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PDIA3 All Species: 26.97
Human Site: T223 Identified Species: 37.08
UniProt: P30101 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P30101 NP_005304.3 505 56782 T223 E D K T V A Y T E Q K M T S G
Chimpanzee Pan troglodytes XP_001159528 485 54945 T203 E D K T V A Y T E Q K M T S G
Rhesus Macaque Macaca mulatta XP_001108948 480 54081 T198 E D K T V A Y T E Q K M T S G
Dog Lupus familis XP_535453 687 75990 I405 E D K T V A Y I E Q K M T S G
Cat Felis silvestris
Mouse Mus musculus P27773 505 56660 T223 E D K T V A Y T E K K M T S G
Rat Rattus norvegicus P11598 505 56605 T223 E D K I V A Y T E K K M T S G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517928 483 54617 T200 E D N T V R Y T E D K I T S G
Chicken Gallus gallus Q8JG64 505 56163 T221 E D S T V K Y T E D K I T S A
Frog Xenopus laevis NP_001080051 502 56103 P219 E D G S V T F P A D E K I T S
Zebra Danio Brachydanio rerio NP_998070 488 54656 T215 E D N V V K Y T E H L S V S S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P54399 496 55763 L225 G E L N E E N L K K F A Q V Q
Honey Bee Apis mellifera XP_623282 490 55838 E220 A N I V K Y D E T M G D I Q E
Nematode Worm Caenorhab. elegans P34329 618 69779 N345 E P K S R T Y N K A A A T S E
Sea Urchin Strong. purpuratus XP_782981 472 51996 G214 E S Q A V F D G A I K K K D V
Poplar Tree Populus trichocarpa
Maize Zea mays P52588 513 57078 V235 V D S K D F D V A A L M K F I
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SRG3 508 56346 E230 D S K D F N G E A L E K F V K
Baker's Yeast Sacchar. cerevisiae P17967 522 58209 V228 A D I A D A D V F E K W L Q V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 91 94.4 70.8 N.A. 93 92.2 N.A. 84.7 80.9 74.6 60 N.A. 32.6 49.5 36.7 50.5
Protein Similarity: 100 92.6 94.8 72.1 N.A. 97 96.2 N.A. 90.3 90.8 88.3 77.2 N.A. 53.4 63.7 50.4 65.9
P-Site Identity: 100 100 100 93.3 N.A. 93.3 86.6 N.A. 73.3 66.6 20 46.6 N.A. 0 0 33.3 20
P-Site Similarity: 100 100 100 93.3 N.A. 100 93.3 N.A. 80 73.3 46.6 46.6 N.A. 20 6.6 46.6 26.6
Percent
Protein Identity: N.A. 34.3 N.A. 35.6 26.8 N.A.
Protein Similarity: N.A. 51 N.A. 54.9 48.4 N.A.
P-Site Identity: N.A. 13.3 N.A. 6.6 20 N.A.
P-Site Similarity: N.A. 13.3 N.A. 20 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 12 0 0 12 0 42 0 0 24 12 6 12 0 0 6 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 6 71 0 6 12 0 24 0 0 18 0 6 0 6 0 % D
% Glu: 71 6 0 0 6 6 0 12 53 6 12 0 0 0 12 % E
% Phe: 0 0 0 0 6 12 6 0 6 0 6 0 6 6 0 % F
% Gly: 6 0 6 0 0 0 6 6 0 0 6 0 0 0 42 % G
% His: 0 0 0 0 0 0 0 0 0 6 0 0 0 0 0 % H
% Ile: 0 0 12 6 0 0 0 6 0 6 0 12 12 0 6 % I
% Lys: 0 0 48 6 6 12 0 0 12 18 59 18 12 0 6 % K
% Leu: 0 0 6 0 0 0 0 6 0 6 12 0 6 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 6 0 42 0 0 0 % M
% Asn: 0 6 12 6 0 6 6 6 0 0 0 0 0 0 0 % N
% Pro: 0 6 0 0 0 0 0 6 0 0 0 0 0 0 0 % P
% Gln: 0 0 6 0 0 0 0 0 0 24 0 0 6 12 6 % Q
% Arg: 0 0 0 0 6 6 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 12 12 12 0 0 0 0 0 0 0 6 0 59 12 % S
% Thr: 0 0 0 42 0 12 0 48 6 0 0 0 53 6 0 % T
% Val: 6 0 0 12 65 0 0 12 0 0 0 0 6 12 12 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 6 0 0 0 % W
% Tyr: 0 0 0 0 0 6 59 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _