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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PDIA3 All Species: 35.45
Human Site: T306 Identified Species: 48.75
UniProt: P30101 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P30101 NP_005304.3 505 56782 T306 F A V A S R K T F S H E L S D
Chimpanzee Pan troglodytes XP_001159528 485 54945 T286 F A V A S R K T F S H E L S D
Rhesus Macaque Macaca mulatta XP_001108948 480 54081 T281 F A V A S R K T F S H E L S D
Dog Lupus familis XP_535453 687 75990 T488 F A V A S R K T F S H E L S D
Cat Felis silvestris
Mouse Mus musculus P27773 505 56660 T306 F A V A S R K T F S H E L S D
Rat Rattus norvegicus P11598 505 56605 T306 F A V A S R K T F S H E L S D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517928 483 54617 T283 F A V A S R K T F G H E L S E
Chicken Gallus gallus Q8JG64 505 56163 T304 F A V A S R K T F G H E L S E
Frog Xenopus laevis NP_001080051 502 56103 S303 F A V A N R K S F G H E V T E
Zebra Danio Brachydanio rerio NP_998070 488 54656 Q297 V A D R Q E F Q D E L E E E F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P54399 496 55763 E296 V T I S S D E E D H T R I F E
Honey Bee Apis mellifera XP_623282 490 55838 D294 F A I S S K D D F Q H E L N D
Nematode Worm Caenorhab. elegans P34329 618 69779 F429 A V A D E E E F A K E L E E L
Sea Urchin Strong. purpuratus XP_782981 472 51996 F285 S I A S A S D F Q R K L D D Y
Poplar Tree Populus trichocarpa
Maize Zea mays P52588 513 57078 I308 D K E I K F L I G D I E A S Q
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SRG3 508 56346 V302 D Q S L A F L V G D A E S S Q
Baker's Yeast Sacchar. cerevisiae P17967 522 58209 N306 G R H A G N L N M K E Q F P L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 91 94.4 70.8 N.A. 93 92.2 N.A. 84.7 80.9 74.6 60 N.A. 32.6 49.5 36.7 50.5
Protein Similarity: 100 92.6 94.8 72.1 N.A. 97 96.2 N.A. 90.3 90.8 88.3 77.2 N.A. 53.4 63.7 50.4 65.9
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 86.6 86.6 60 13.3 N.A. 6.6 53.3 0 0
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 93.3 93.3 93.3 13.3 N.A. 40 80 6.6 13.3
Percent
Protein Identity: N.A. 34.3 N.A. 35.6 26.8 N.A.
Protein Similarity: N.A. 51 N.A. 54.9 48.4 N.A.
P-Site Identity: N.A. 13.3 N.A. 13.3 6.6 N.A.
P-Site Similarity: N.A. 13.3 N.A. 20 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 6 65 12 59 12 0 0 0 6 0 6 0 6 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 12 0 6 6 0 6 12 6 12 12 0 0 6 6 42 % D
% Glu: 0 0 6 0 6 12 12 6 0 6 12 77 12 12 24 % E
% Phe: 59 0 0 0 0 12 6 12 59 0 0 0 6 6 6 % F
% Gly: 6 0 0 0 6 0 0 0 12 18 0 0 0 0 0 % G
% His: 0 0 6 0 0 0 0 0 0 6 59 0 0 0 0 % H
% Ile: 0 6 12 6 0 0 0 6 0 0 6 0 6 0 0 % I
% Lys: 0 6 0 0 6 6 53 0 0 12 6 0 0 0 0 % K
% Leu: 0 0 0 6 0 0 18 0 0 0 6 12 53 0 12 % L
% Met: 0 0 0 0 0 0 0 0 6 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 6 6 0 6 0 0 0 0 0 6 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 6 0 % P
% Gln: 0 6 0 0 6 0 0 6 6 6 0 6 0 0 12 % Q
% Arg: 0 6 0 6 0 53 0 0 0 6 0 6 0 0 0 % R
% Ser: 6 0 6 18 59 6 0 6 0 36 0 0 6 59 0 % S
% Thr: 0 6 0 0 0 0 0 48 0 0 6 0 0 6 0 % T
% Val: 12 6 53 0 0 0 0 6 0 0 0 0 6 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _