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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP2R1A
All Species:
18.18
Human Site:
S314
Identified Species:
30.77
UniProt:
P30153
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P30153
NP_055040.2
589
65309
S314
K
E
F
C
E
N
L
S
A
D
C
R
E
N
V
Chimpanzee
Pan troglodytes
XP_001174531
629
69337
S354
K
E
F
C
E
N
L
S
A
D
C
R
E
N
V
Rhesus Macaque
Macaca mulatta
XP_001116610
587
65093
S314
K
E
F
C
E
N
L
S
A
D
C
R
E
N
V
Dog
Lupus familis
XP_541451
590
65427
S314
K
E
F
C
E
N
L
S
A
D
C
R
E
N
V
Cat
Felis silvestris
Mouse
Mus musculus
Q7TNP2
601
65931
P326
R
E
L
C
E
N
L
P
A
E
G
R
E
T
V
Rat
Rattus norvegicus
Q4QQT4
601
65988
P326
R
E
L
C
E
N
L
P
T
E
G
R
E
T
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519495
592
65127
P317
K
E
L
C
E
N
L
P
P
D
G
R
E
T
I
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001080135
589
65415
S314
K
E
F
C
E
N
L
S
A
D
C
R
E
N
V
Zebra Danio
Brachydanio rerio
NP_001005590
589
65140
P314
K
V
F
C
E
N
L
P
E
D
S
R
E
T
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P36179
591
65405
D316
K
D
F
C
A
N
L
D
K
V
N
Q
V
Q
I
Honey Bee
Apis mellifera
XP_001120202
590
65684
D316
R
D
F
C
Q
N
L
D
K
F
N
Q
E
S
I
Nematode Worm
Caenorhab. elegans
Q09543
590
66130
P316
Q
E
F
A
L
N
L
P
E
D
K
R
Q
N
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38950
587
65580
C308
A
G
K
V
T
K
F
C
R
I
L
N
P
E
I
Baker's Yeast
Sacchar. cerevisiae
P31383
635
70933
K349
K
Q
V
S
G
F
A
K
F
L
N
D
P
S
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.6
99.1
98.8
N.A.
84.6
85
N.A.
83.1
N.A.
96
87.6
N.A.
74.4
80.1
62.2
N.A.
Protein Similarity:
100
93.6
99.1
99.1
N.A.
92
92.1
N.A.
91.5
N.A.
98.3
93.5
N.A.
84.9
89.1
76
N.A.
P-Site Identity:
100
100
100
100
N.A.
60
53.3
N.A.
60
N.A.
100
60
N.A.
33.3
33.3
46.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
73.3
66.6
N.A.
66.6
N.A.
100
66.6
N.A.
53.3
73.3
66.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
57.7
42.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
76.2
61.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
8
0
8
0
43
0
0
0
0
0
0
% A
% Cys:
0
0
0
79
0
0
0
8
0
0
36
0
0
0
0
% C
% Asp:
0
15
0
0
0
0
0
15
0
58
0
8
0
0
0
% D
% Glu:
0
65
0
0
65
0
0
0
15
15
0
0
72
8
0
% E
% Phe:
0
0
65
0
0
8
8
0
8
8
0
0
0
0
0
% F
% Gly:
0
8
0
0
8
0
0
0
0
0
22
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
50
% I
% Lys:
65
0
8
0
0
8
0
8
15
0
8
0
0
0
0
% K
% Leu:
0
0
22
0
8
0
86
0
0
8
8
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
86
0
0
0
0
22
8
0
43
0
% N
% Pro:
0
0
0
0
0
0
0
36
8
0
0
0
15
0
0
% P
% Gln:
8
8
0
0
8
0
0
0
0
0
0
15
8
8
0
% Q
% Arg:
22
0
0
0
0
0
0
0
8
0
0
72
0
0
0
% R
% Ser:
0
0
0
8
0
0
0
36
0
0
8
0
0
15
0
% S
% Thr:
0
0
0
0
8
0
0
0
8
0
0
0
0
29
0
% T
% Val:
0
8
8
8
0
0
0
0
0
8
0
0
8
0
50
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _