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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP2R1A
All Species:
13.64
Human Site:
Y169
Identified Species:
23.08
UniProt:
P30153
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P30153
NP_055040.2
589
65309
Y169
V
K
A
E
L
R
Q
Y
F
R
N
L
C
S
D
Chimpanzee
Pan troglodytes
XP_001174531
629
69337
Y209
V
K
A
E
L
R
Q
Y
F
R
N
L
C
S
D
Rhesus Macaque
Macaca mulatta
XP_001116610
587
65093
Y169
V
K
A
E
L
R
Q
Y
F
R
N
L
C
S
D
Dog
Lupus familis
XP_541451
590
65427
Y169
V
K
A
E
L
R
Q
Y
F
R
N
L
C
S
D
Cat
Felis silvestris
Mouse
Mus musculus
Q7TNP2
601
65931
H181
V
K
A
E
I
R
Q
H
F
R
S
L
C
S
D
Rat
Rattus norvegicus
Q4QQT4
601
65988
H181
V
K
A
E
I
R
Q
H
F
R
S
L
C
S
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519495
592
65127
H172
V
R
A
E
I
R
Q
H
F
R
S
L
C
A
D
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001080135
589
65415
H169
V
K
A
E
L
R
Q
H
F
R
N
L
C
S
D
Zebra Danio
Brachydanio rerio
NP_001005590
589
65140
H169
V
K
A
E
I
R
Q
H
F
R
T
L
C
S
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P36179
591
65405
N171
V
K
A
E
L
R
A
N
F
R
K
L
C
Q
D
Honey Bee
Apis mellifera
XP_001120202
590
65684
H171
V
K
A
C
L
R
N
H
F
R
N
L
C
Q
D
Nematode Worm
Caenorhab. elegans
Q09543
590
66130
M171
I
K
S
E
L
K
S
M
F
R
T
L
C
R
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38950
587
65580
L167
L
K
T
E
L
R
S
L
Y
T
Q
L
C
Q
D
Baker's Yeast
Sacchar. cerevisiae
P31383
635
70933
A196
S
L
R
K
N
I
L
A
L
Y
L
Q
L
A
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.6
99.1
98.8
N.A.
84.6
85
N.A.
83.1
N.A.
96
87.6
N.A.
74.4
80.1
62.2
N.A.
Protein Similarity:
100
93.6
99.1
99.1
N.A.
92
92.1
N.A.
91.5
N.A.
98.3
93.5
N.A.
84.9
89.1
76
N.A.
P-Site Identity:
100
100
100
100
N.A.
80
80
N.A.
66.6
N.A.
93.3
80
N.A.
73.3
73.3
53.3
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
N.A.
100
93.3
N.A.
73.3
80
73.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
57.7
42.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
76.2
61.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
46.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
60
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
79
0
0
0
8
8
0
0
0
0
0
15
0
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
93
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
93
% D
% Glu:
0
0
0
86
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
86
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
43
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
29
8
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
86
0
8
0
8
0
0
0
0
8
0
0
0
0
% K
% Leu:
8
8
0
0
65
0
8
8
8
0
8
93
8
0
0
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
8
8
0
0
43
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
65
0
0
0
8
8
0
22
8
% Q
% Arg:
0
8
8
0
0
86
0
0
0
86
0
0
0
8
0
% R
% Ser:
8
0
8
0
0
0
15
0
0
0
22
0
0
58
0
% S
% Thr:
0
0
8
0
0
0
0
0
0
8
15
0
0
0
0
% T
% Val:
79
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
29
8
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _