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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP2R1B
All Species:
17.58
Human Site:
S43
Identified Species:
29.74
UniProt:
P30154
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P30154
NP_002707.3
601
66214
S43
D
V
Q
L
R
L
N
S
I
K
K
L
S
T
I
Chimpanzee
Pan troglodytes
XP_001174531
629
69337
S71
P
I
S
L
R
L
N
S
I
K
K
L
S
T
I
Rhesus Macaque
Macaca mulatta
XP_001116610
587
65093
A39
I
K
K
L
S
T
I
A
L
A
L
G
V
E
R
Dog
Lupus familis
XP_862393
601
66100
S43
D
V
Q
L
R
L
N
S
I
K
K
L
S
T
I
Cat
Felis silvestris
Mouse
Mus musculus
Q7TNP2
601
65931
S43
D
V
Q
L
R
L
N
S
I
K
K
L
S
T
I
Rat
Rattus norvegicus
Q4QQT4
601
65988
S43
D
V
Q
L
R
L
N
S
I
K
K
L
S
T
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519495
592
65127
I41
S
I
K
K
L
S
T
I
A
L
A
L
G
A
E
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001082552
589
65370
I38
S
I
K
K
L
S
T
I
A
L
A
L
G
V
E
Zebra Danio
Brachydanio rerio
NP_001005590
589
65140
I38
S
I
K
K
L
S
T
I
A
L
A
L
G
V
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P36179
591
65405
A41
I
K
K
L
S
T
I
A
L
A
L
G
E
E
R
Honey Bee
Apis mellifera
XP_001120202
590
65684
A41
I
K
K
L
S
T
I
A
L
A
L
G
I
E
R
Nematode Worm
Caenorhab. elegans
Q09543
590
66130
I40
S
I
R
K
L
S
T
I
A
L
A
L
G
V
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38845
588
65476
A39
R
L
S
T
I
A
R
A
L
G
E
E
R
T
R
Baker's Yeast
Sacchar. cerevisiae
P31383
635
70933
A57
D
I
A
N
R
V
E
A
M
K
K
L
D
T
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79.3
84.1
96.6
N.A.
95
95.8
N.A.
87.1
N.A.
87.3
87.1
N.A.
70.5
75.2
60.9
N.A.
Protein Similarity:
100
86.1
90.8
98.8
N.A.
98.3
98.5
N.A.
93.8
N.A.
93.1
92.8
N.A.
82.5
85.5
74.7
N.A.
P-Site Identity:
100
80
6.6
100
N.A.
100
100
N.A.
6.6
N.A.
6.6
6.6
N.A.
6.6
6.6
6.6
N.A.
P-Site Similarity:
100
86.6
26.6
100
N.A.
100
100
N.A.
20
N.A.
20
20
N.A.
26.6
26.6
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
56
43.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
72.3
63.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
46.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
8
0
36
29
22
29
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
36
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% D
% Glu:
0
0
0
0
0
0
8
0
0
0
8
8
8
22
29
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
8
0
22
29
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
22
43
0
0
8
0
22
29
36
0
0
0
8
0
43
% I
% Lys:
0
22
43
29
0
0
0
0
0
43
43
0
0
0
0
% K
% Leu:
0
8
0
58
29
36
0
0
29
29
22
72
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
0
36
0
0
0
0
0
0
0
0
% N
% Pro:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
29
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
8
0
8
0
43
0
8
0
0
0
0
0
8
0
29
% R
% Ser:
29
0
15
0
22
29
0
36
0
0
0
0
36
0
0
% S
% Thr:
0
0
0
8
0
22
29
0
0
0
0
0
0
50
0
% T
% Val:
0
29
0
0
0
8
0
0
0
0
0
0
8
22
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _