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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CDC27 All Species: 6.36
Human Site: S351 Identified Species: 11.67
UniProt: P30260 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P30260 NP_001107563.1 824 91867 S351 P I L A Q T Q S S G P Q T S T
Chimpanzee Pan troglodytes XP_511624 824 91839 S351 P I L A Q T Q S S G P Q T S T
Rhesus Macaque Macaca mulatta XP_001115994 824 91959 E351 I L L P Q P P E Q G P R S S T
Dog Lupus familis XP_548047 825 91842 Q351 P I L V A Q T Q S S G P Q T S
Cat Felis silvestris
Mouse Mus musculus NP_663411 825 91824 Q351 P V L V A Q T Q S S G P Q T S
Rat Rattus norvegicus NP_001019964 824 91645 Q351 P V L V A Q T Q S S G P Q T S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520967 385 43892
Chicken Gallus gallus NP_001006331 833 92606 T351 T P I L V A Q T Q S S G P Q T
Frog Xenopus laevis NP_001085568 833 92363 Q351 P V L L V Q T Q G S G P Q T S
Zebra Danio Brachydanio rerio NP_958857 790 87878 N350 N S R E V I P N P F I Q T Q T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648093 900 101266 Y350 T P V M N I S Y S P M P Q M L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786824 824 91473 P349 S P V Q L L F P S A H G V R R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P38042 758 85418 L318 N S K T S S A L P N N I S M N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 96.3 99.1 N.A. 96.9 97.4 N.A. 43.6 94.5 89.6 76.5 N.A. 39.2 N.A. N.A. 49.2
Protein Similarity: 100 99.8 97.2 99.2 N.A. 98.6 98.5 N.A. 45.2 96.6 94.5 84.3 N.A. 57.4 N.A. N.A. 67.2
P-Site Identity: 100 100 40 26.6 N.A. 20 20 N.A. 0 13.3 13.3 20 N.A. 6.6 N.A. N.A. 6.6
P-Site Similarity: 100 100 60 40 N.A. 40 40 N.A. 0 26.6 33.3 26.6 N.A. 13.3 N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 23.7 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 39.2 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 16 24 8 8 0 0 8 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 8 0 0 0 8 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 8 0 0 8 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 8 24 31 16 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % H
% Ile: 8 24 8 0 0 16 0 0 0 0 8 8 0 0 0 % I
% Lys: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 8 54 16 8 8 0 8 0 0 0 0 0 0 8 % L
% Met: 0 0 0 8 0 0 0 0 0 0 8 0 0 16 0 % M
% Asn: 16 0 0 0 8 0 0 8 0 8 8 0 0 0 8 % N
% Pro: 47 24 0 8 0 8 16 8 16 8 24 39 8 0 0 % P
% Gln: 0 0 0 8 24 31 24 31 16 0 0 24 39 16 0 % Q
% Arg: 0 0 8 0 0 0 0 0 0 0 0 8 0 8 8 % R
% Ser: 8 16 0 0 8 8 8 16 54 39 8 0 16 24 31 % S
% Thr: 16 0 0 8 0 16 31 8 0 0 0 0 24 31 39 % T
% Val: 0 24 16 24 24 0 0 0 0 0 0 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _